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老年良性前列腺增生患者微创术后发生性功能障碍的影响因素

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目的:探讨老年良性前列腺增生患者微创术后发生性功能障碍的影响因素.方法:回顾性选取赣南医学院附属兴国医院 2018 年 12 月—2021 年 12 月赣南医学院附属兴国医院 82 例行微创术的老年良性前列腺增生患者的临床资料,术后随访 12 个月,统计分析性功能障碍发生情况.将发生性功能障碍的患者设置为性功能障碍组,未发生性功能障碍的患者设置为无性功能障碍组.采用logistic回归分析法分析老年良性前列腺增生患者微创术后发生性功能障碍的影响因素.结果:随访 12 个月后,在 82 例接受微创术的老年良性前列腺增生患者中,发生性功能障碍的患者 28 例,发生率为 34.15%.两组术前体重指数(BMI)、病程、吸烟史、饮酒史、高血压对比,差异均无统计学意义(P>0.05);性功能障碍组术前国际前列腺症状评分(IPSS)评分、年龄均高于无性功能障碍组,抑郁、焦虑占比均高于无性功能障碍组(P<0.05),前列腺素E2、一氧化氮合成酶、一氧化氮水平均低于无性功能障碍组(P<0.05).logistic回归分析结果显示,术前IPSS评分、年龄、抑郁、焦虑、前列腺素E2、一氧化氮合成酶、一氧化氮水平均为老年良性前列腺增生患者微创术后发生性功能障碍的影响因素(P<0.05).结论:术前IPSS评分、年龄、抑郁、焦虑、前列腺素E2、一氧化氮合成酶、一氧化氮水平均为老年良性前列腺增生患者微创术后发生性功能障碍的影响因素,可为评估老年良性前列腺增生微创术后性功能障碍的发生风险提供可靠的预测方式.
Influencing Factors of Sexual Dysfunction in Elderly Patients with Benign Prostatic Hyperplasia after Minimally Invasive Surgery
Objective:To investigate the influencing factors sexual dysfunction in elderly patients with benign prostatic hyperplasia after minimally invasive surgery.Method:A total of 82 elderly patients with benign prostatic hyperplasia who underwent microsurgery in Xingguo Hospital Affiliated to Gannan Medical College from December 2018 to December 2021 were retrospectively selected,followed up for 12 months after surgery,and the incidence of sexual dysfunction was statistically analyzed.The patients with sexual dysfunction were set into the sexual dysfunction group,and the patients without sexual dysfunction were set into the without sexual dysfunction group.logistic regression analysis was used to analyze the influencing factors of sexual dysfunction in elderly patients with benign prostatic hyperplasia after minimally invasive surgery.Result:After 12 months of follow-up,28 cases of sexual dysfunction occurred in 82 patients with benign prostatic hyperplasia,with an incidence of 34.15%.There were no significant differences in preoperative body mass index(BMI),course of disease,smoking history,drinking history and hypertension between the two groups(P>0.05);the international prostate symptom score(IPSS),age in the sexual dysfunction group were higher than those in the without sexual dysfunction group,the proportion of depression and anxiety were higher than those in the without sexual dysfunction group(P<0.05);the levels of prostaglandin E2,nitric oxide synthase and nitric oxide were lower than those of without sexual dysfunction group(P<0.05).logistic regression analysis showed that preoperative IPSS score,age,depression,anxiety,prostaglandin E2,nitric oxide synthase and nitric oxide level were influential factors for sexual dysfunction in elderly patients with benign prostatic hyperplasia after minimally invasive surgery(P<0.05).Conclusion:Preoperative IPSS score,age,depression,anxiety,prostaglandin E2,nitric oxide synthase,and nitric oxide levels are influencing factors for the occurrence of sexual dysfunction in elderly patients with benign prostatic hyperplasia after minimally invasive surgery,which can provide a reliable prediction method for assessing the risk of sexual dysfunction in elderly patients with benign prostatic hyperplasia after minimally invasive surgery.

Prostaglandin E2Nitric oxide synthaseNitric oxideSexual dysfunctionBenign prostatic hyperplasia

谢婷、刘丽娟、谢锌锦、江沛源

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赣南医学院附属兴国医院泌尿外科 江西 赣州 342400

赣南医学院附属兴国医院血透室 江西 赣州 342400

前列腺素E2 一氧化氮合成酶 一氧化氮 性功能障碍 良性前列腺增生

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(13)
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