Effect of Adaptive Support Ventilation on Pulmonary Injury and Weaning Success Rate in Patients with COPD and Respiratory Failure
Objective:To observe the effect of adaptive support ventilation on pulmonary injury and weaning success rate in patients with chronic obstructive pulmonary disease(COPD)complicated with respiratory failure.Method:A total of 80 patients with COPD and respiratory failure undergoing mechanical ventilation treatment in Nanchang Hongdu Hospital of TCM from August 2020 to August 2023 were selected as the subjects,and were devided into group A(adaptive support ventilation model)and group B(synchronous intermittent instruction+pressure supported ventilation model)according to the random number table method,with 40 cases in each group.The two groups were compared in terms of blood gas indicators,respiratory function,acute physiology and chronic health evaluation Ⅱ(APACHEⅡ)score,adverse events and weaning status.Result:After treatment,there were no statistically significant differences in arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),power of hydrogen(pH)and score of APACHEⅡ between the two groups(P>0.05).The success rate of one-time weaning,peak time to reach ratio(TPTEF/TE)and peak volume to reach ratio(VPEF/VE)in group A were higher than those in group B,the inspiratory and expiratory ratio(TI/TE)and respiratory rate(RR)were lower than those in group B,the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse events between both groups during treatment(P>0.05).Conclusion:Adaptive support ventilation for patients with COPD complicated with respiratory failure can better improve the respiratory function and increase the success rate of weaning one-time.
Adaptive support ventilationChronic obstructive pulmonary diseaseRespiratory failure
万方数据
维普
