首页|高剂量双联疗法联合甘海胃康胶囊治疗幽门螺杆菌感染相关性胃炎的效果

高剂量双联疗法联合甘海胃康胶囊治疗幽门螺杆菌感染相关性胃炎的效果

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目的:探讨对幽门螺杆菌(Helicobacter pylori,Hp)感染相关性胃炎患者采用高剂量双联疗法联合甘海胃康胶囊治疗的临床效果.方法:按照治疗方式的不同将 2022 年 4 月—2023 年 8 月瑞金市人民医院收治的Hp感染相关性胃炎患者分为对照组和试验组,各 36 例.对照组施以高剂量双联疗法疗,试验组则在此基础上联合甘海胃康胶囊治疗,均连续治疗 30 d.比较两组临床效果、Hp根除率、中医症候积分.结果:和对照组相比,试验组总有效率、Hp根除率均较高,差异均有统计学意义(P<0.05).治疗后,两组中医症候各项积分均较治疗前降低,与对照组相比,试验组中医症候各项积分均较低(P<0.05).结论:将高剂量双联疗法联合甘海胃康胶囊应用于Hp感染相关性胃炎患者的治疗中,临床效果显著,且在促进患者临床症状改善,提高Hp根除率方面具有积极意义.
Effect of High-dose Dual Therapy Combined with Ganhai Weikang Capsules in the Treatment of Helicobacter Pylori Infection Associated Gastritis
Objective:To explore the clinical efficacy of high-dose dual therapy combined with Ganhai Weikang Capsules on Helicobacter pylori(Hp)infection associated gastritis.Method:According to different treatment methods,patients with Hp infection associated gastritis admitted to Ruijin People's Hospital from April 2022 to August 2023 were divided into a control group and an experimental group,with 36 cases in each group.The control group was treated with high-dose dual therapy,while the experimental group was treated with Ganhai Weikang Capsules on this basis,both of which were continuously treated for 30 days.The clinical efficacy,Hp eradication rate,traditional Chinese medicine syndrome before and after treatment between the two groups were compared.Result:Compared with the control group,total effective rate and Hp eradication rate in the experimental group were higher,the differences were statistically significant(P<0.05).After treatment,both groups of traditional Chinese medicine syndrome scores were decreased compared to those before treatment,and compared with the control group,those in the experimental group were lower(P<0.05).Conclusion:The application of high-dose dual therapy combined with Ganhai Weikang Capsules in the treatment of Hp infection associated gastritis patients has significant clinical effects,and has positive significance in promoting the improvement of clinical symptoms and increasing the eradication rate of Hp.

GastritisHelicobacter pylori infectionGanhai Weikang CapsulesDual therapy

黄海华、詹先峰、胡永生

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瑞金市人民医院消化内科 江西 瑞金 342500

瑞金市人民医院感染科 江西 瑞金 342500

胃炎 幽门螺杆菌感染 甘海胃康胶囊 双联疗法

赣州市指导性科技计划

GZ2023ZSF575

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(14)
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