Effect of Complex Packing Estradiol Tablets/Estradiol and Dydrogesterone Tablets Combined with Estradiol Gel on Endometrium of Patients after High-risk Induced Abortion
Objective:To investigate the effect of Complex Packing Estradiol Tablets/Estradiol and Dydrogesterone Tablets combined with Estradiol Gel on endometrium of patients after high-risk induced abortion.Method:A total of 182 patients with high-risk induced abortion who were treated in Maternity and Child Care Center of Xinyu from January 2021 to January 2023 were selected as the study objects,and were divided into control group(n=91)and observation group(n=91)according to random allocation scheme.The control group was given Guizhi Fuling Capsules,and the observation group was given Complex Packing Estradiol Tablets/Estradiol and Dydrogesterone Tablets combined with Estradiol Gel on the basis of Guizhi Fuling Capsules.Menstruation,endometrial thickness and adverse events were compared between the two groups.Result:The time of menstrual regain in the observation group was earlier than that in the control group,and the rate of menstrual volume loss was lower than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the recurrence rate of menstrual cycle between the two groups(P>0.05).There was no significant difference in endometrial thickness between the two groups before treatment(P>0.05);after treatment,endometrial thickness in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).The incidence of adverse events was 8.79%in the observation group and 3.30%in the control group,there was no significant difference between the two groups(字2=2.419,P=0.120).Conclusion:After high-risk induced abortion,Complex Packing Estradiol Tablets/Estradiol and Dydrogesterone Tablets combined with Estradiol Gel can effectively repair endometrium,promote menstrual recovery,and do not increase the occurrence of adverse events.
High-risk induced abortionComplex Packing Estradiol Tablets/Estradiol and Dydrogesterone TabletsEstradiol GelEndometrium
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