Effect of Nalbuphine Combined with Ropivacaine Abdominal Transversal Fascia Block Multimodal Analgesia on Emergence Agitation in Children Undergoing Laparoscopic Operation under General Anesthesia
Objective:To explore the effect of Nalbuphine combined with Ropivacaine abdominal transversal fascia block multimodal analgesia on emergence agitation in children undergoing laparoscopic operation under general anesthesia.Method:A total of 80 children received laparoscopic operation under general anesthesia in the Matemity and Child Health Hospital of Ji'an from June 2022 to August 2023 were selected as the study objects,and were divided into control group and observation group by random number table method,with 40 cases in each group.In the control group,after tracheal intubation,bilateral false abdominal transversal fascia block was performed under the guidance of ultrasound(0.5 mL/kg Sodium Chloride was injected,0.2 mg/kg Nalbuphine was injected intravenously 15 minutes before the end of the operation).In the observation group,after tracheal intubation,bilateral abdominal transversal fascia block was performed under the guidance of ultrasound(0.5 mL/kg Ropivacaine was injected,0.2 mg/kg Nalbuphine was injected intravenously 15 minutes before the end of the operation).The sign indexes,agitation score,sedation score,analgesia score,extubation time,recovery time and adverse reactions were compared between the two groups.Result:The mean arterial pressure(MAP)and heart rate(HR)at T2 and T3 in observation group were lower than those in control group,the differences were statistically significant(P<0.05).The extubation time and recovery time of observation group were earlier than those of control group,and Ramsay sedation score was higher than that of control group,the differences were statistically significant(P<0.05).The incidence of agitation in observation group(2.50%)was lower than that in control group(22.50%),the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reaction between the two groups(P>0.05).Conclusion:Nalbuphine combined with Ropivacaine abdominal transversal fascia block multimodal analgesia can reduce the incidence of emergence agitation on the basis of stable hemodynamics,has good analgesic and sedative effects,and does not affect the extubation time and recovery time.
Laparoscopic operationGeneral anesthesiaEmergence agitationNalbuphineRopivacaineAbdominal transversal fascia blockAnalgesia
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