Evaluation Value of Multi-slice Spiral CT Combined with MR Diffusion Weighted Imaging in TACE Treatment of Patients with Liver Cancer
Objective:To investigate the evaluation value of multi-slice spiral CT(MSCT)combined with MR diffusion weighted imaging in transcatheter arterial chemoembolization(TACE)treatment of patients with liver cancer.Method:A total of 102 patients with liver cancer admitted to People's Hospital of Hai'an City from February 2018 to February 2023 were prospectively selected as the study objects.All patients were examined by MSCT and MRI before and after TACE treatment,and the factors affecting the therapeutic effect of TACE on patients with liver cancer were analyzed.Result:In 102 patients with liver cancer,3 months after TACE treatment,13 cases of complete remission(CR),28 cases of partial remission(PR),41 cases of stable disease(SD),20 cases of progression disease(PD),41 cases of CR and PR were recorded as objective remission group,and the remaining 61 cases were recorded as non-remission group.After treatment,protal vein perfusion(PVP)and apparent diffusion coeffecient(ADC)in objective remission group were higher than those in non-remission group,hepatic arteral perfusion(HAP)and Kep were lower than those in non-remission group(P<0.05).logistic regression analysis was performed taking TACE treatment effect of patients with liver cancer as dependent variable(objective response=0,non-response=1),and PVP,ADC,Kep,HAP as independent variables(valuated as original value).The results showed that HAP and ADC were the factors affecting the therapeutic effect of TACE in patients with liver cancer(P<0.05).ROC curve results showed that the sensitivity of HAP,ADC and their combination in evaluating the therapeutic effect of TACE in patients with liver cancer was 74.45%,79.63%,and 74.45%respectively,the specificity was 74.38%,76.99%,89.69%respectively,and the AUC was 0.749,0.740,0.884 respectively.Conclusion:HAP and ADC are related to TACE treatment effect in patients with liver cancer,and their combination evaluation of TACE treatment effect in patients with liver cancer has the highest efficacy.
万方数据
维普
