Analysis of Risk Factors of Dialysis Pericarditis in Hemodialysis Patients with Uremia
Objective:To investigate the risk factors of dialysis pericarditis in hemodialysis patients with uremia.Method:A total of 240 uremia patients admitted to Jiangxi Chest Hospital for hemodialysis treatment from March 2019 to November 2022 were retrospectively selected as the study objects.According to the occurrence of dialysis pericarditis,uremia patients were divided into pericarditis group(dialysis pericarditis)and control group(no dialysis pericarditis).logistic regression was used to screen the risk factors of dialysis pericarditis in hemodialysis patients with uremia.Result:Among 240 patients with uremia,41 patients had dialysis pericarditis,and the incidence of dialysis pericarditis was 17.08%(41/240).There were no significant differences in age,sex,primary disease,vascular access,body mass index,blood calcium,blood phosphorus,blood magnesium,drinking history and smoking history between pericarditis group and control group(P>0.05).In pericarditis group,the use of heparin,dialysis time≥2 years,urea clearance index<1.2,the proportion of anemia,hypoproteinemia and the level of chemokine ligand 18(CCL18)were higher than those in control group,with statistical significance(P<0.05).logistic regression analysis showed that heparin was used[OR=3.665,95%CI(1.515,8.865)]and dialysis duration≥2 years[OR=3.239,95%CI(1.366,7.682)],urea clearance index<1.2[OR=4.428,95%CI(1.651,11.876)],anemia[OR=3.474,95%CI(1.290,9.351)],hypoproteinemia[OR=3.194,95%CI(1.130,9.031)]and higher CCL18 level[OR=1.095,95%CI(1.052,1.139)]were risk factors for dialysis pericarditis in hemodialysis patients with uremia(P<0.05).Conclusion:Heparin use,dialysis duration≥2 years,urea clearance index<1.2,anemia,hypoproteinemia and high level of CCL18 are risk factors for dialysis pericarditis in patients with uremic hemodialysis.The above risk factors should be considered in the clinical development of prevention and treatment strategies to reduce the occurrence of dialysis pericarditis.
万方数据
维普
