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肝硬化门静脉高压相关并发症的危险因素分析

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目的:分析肝硬化门静脉高压相关并发症发生的危险因素.方法:回顾性分析 2020 年1 月—2023 年 1 月郴州市第二人民医院收治的 322 例肝硬化门静脉高压患者的临床资料,统计其并发症发生情况,另收集患者的年龄、性别等资料,统计分析并发症发生的危险因素.结果:322 例肝硬化门静脉高压患者中,发生并发症的有 58 例,发生率为 18.01%(58/322).单因素分析显示,发生组的肝功能Child-Pugh分级为C级占比、有红色征占比均高于未发生组,门静脉内径高于未发生组,PT长于未发生组,ALB低于未发生组,差异均有统计学意义(P<0.05).logistic回归分析显示,肝功能Child-Pugh分级为C级[OR=8.566,95%CI(4.535,16.181)]、有红色征[OR=10.817,95%CI(5.490,21.316)]、门静脉内径高[OR=1.791,95%CI(1.430,2.244)]、PT延长[OR=1.804,95%CI(1.496,2.176)]为肝硬化门静脉高压并发症发生的危险因素,ALB水平[OR=0.912,95%CI(0.852,0.977)]为肝硬化门静脉高压并发症发生的保护因素(P<0.05).结论:肝功能Child-Pugh分级为C级、有红色征、门静脉内径高、PT延长为肝硬化门静脉高压并发症发生的危险因素,ALB水平高为肝硬化门静脉高压并发症发生的保护因素.
Risk Factors Analysis of Complications Related to Portal Hypertension in Liver Cirrhosis
Objective:To analyze the risk factors for complications related to portal hypertension in liver cirrhosis.Method:A retrospective analysis was conducted on the clinical data of 322 patients with portal hypertension in liver cirrhosis admitted to Chenzhou City NO.2 People's Hospital from January 2020 to January 2023,the incidence of complications was statisticed,and data such as age and gender were collected,the risk factors for incidence of complications were statistically analyzed.Result:Among the 322 patients with portal hypertension in liver cirrhosis,58 had complications,incidence rate of 18.01%(58/322).Univariate analysis showed that proportion of Child-Pugh grade C liver function,proportion of red signs in the incidence group were higher than those in the non incidence group,portal vein diameter was higher than that in the non incidence group,PT was longer than that in the non incidence group,and ALB was lower than that in the non incidence group(P<0.05).logistic regression analysis shows that the Child Pugh grading of liver function as grade C[OR=8.566,95%CI(4.535,16.181)],with red sign[OR=10.817,95%CI(5.490,21.316)],high portal vein diameter[OR=1.791,95%CI(1.430,2.244)],PT extension[OR=1.804,95%CI(1.496,2.176)]were risk factors for complications of portal hypertension in liver cirrhosis,high ALB level[OR=0.912,95%CI(0.852,0.977)]was protective factors for the occurrence of complications of liver cirrhosis with portal hypertension(P<0.05).Conclusion:The Child-Pugh grading of liver function as grade C,with red signs,high portal vein diameter,and prolonged PT are risk factors for the occurrence of complications of portal hypertension in liver cirrhosis,high ALB level is protective factor for the occurrence of complications of portal hypertension in liver cirrhosis.

Portal hypertension in liver cirrhosisComplicationsRisk factors

贺鹏志、宁峰

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郴州市第二人民医院肝病一科 湖南 郴州 423000

肝硬化门静脉高压 并发症 危险因素

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(14)
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