Research Progress of Non-alcoholic Fatty Liver Disease and Related Hepatocellular Carcinoma
Non-alcoholic fatty liver disease(NAFLD)is a metabolic disease dominated by fat deposition in the liver,which can lead to the occurrence and development of hepatic steatosis,cirrhosis and hepatocellular carcinoma(HCC).NAFLD and NAFLD-related HCC share similar diversified pathogenesis,including insulin resistance,fat metabolism,genetic susceptibility,immune dysregulation,intestinal flora disorder,iron deposition,and so on.In recent years,with the increase of the prevalence of NAFLD,the prevalence of NAFLD-related HCC has also increased year by year,so early monitoring and prevention of NAFLD-related HCC are particularly important.This article reviews the epidemiology,pathogenesis,surveillance and prevention of NAFLD-related HCC,which lays a foundation for understanding the current situation and prevention of NAFLD-related HCC.
Non-alcoholic fatty liver diseaseHepatocellular carcinomaMolecular mechanismsProgression of disease
万方数据
维普
