首页|不同剂量阿芬太尼在无痛取卵术中的应用研究

不同剂量阿芬太尼在无痛取卵术中的应用研究

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目的:研究不同剂量阿芬太尼在无痛取卵术中的应用效果.方法:选择2022年8月—2023年8 月于井冈山大学附属医院行无痛取卵术的 200 例患者,按随机数字表法将其分为P组、A1 组、A2 组、A3 组,各 50 例.A1 组采用 5 μg/kg阿芬太尼复合丙泊酚麻醉,A2 组采用 7 μg/kg阿芬太尼复合丙泊酚麻醉,A3 组采用 9 μg/kg阿芬太尼复合丙泊酚麻醉,P组采用丙泊酚麻醉.比较四组血流动力学[平均动脉压(MAP)、心率(HR)]、苏醒时间、达离院标准时间、取卵时间、不良反应及满意度.结果:T0、T1、T2 时,四组MAP及HR水平比较,差异均无统计学意义(P>0.05).A1 组、A2 组与A3 组的苏醒时间、达离院标准时间均短于P组,A1 组、A2 组的呼吸抑制发生率低于P组与A3 组,A2 组与A3 组的体动发生率低于P组与A1 组,A1 组、A2 组与A3 组的满意度均高于P组,差异均有统计学意义(P<0.05).A1 组、A2 组与A3 组的苏醒时间、达离院标准时间及满意度比较,四组取卵时间、恶心呕吐发生率比较,A1 组与A2 组呼吸抑制发生率比较,A2 组与A3 组的体动发生率比较,差异均无统计学意义(P>0.05).结论:无痛取卵术中采用 7 μg/kg阿芬太尼复合丙泊酚麻醉效果良好,患者术后苏醒质量良好、满意度高,且患者血流动力学无明显变化,可减少不良反应的发生.
Application Study on the Different Doses of Alfentanil in Painless Egg Extraction Surgery
Objective:To study the application effect of different doses of Alfentanil in painless egg retrieval surgery.Method:A total of 200 patients who underwent painless egg retrieval surgery in Jinggangshan University Affiliated Hospital from August 2022 to August 2023 were selected and divided into group P and group A1,group A2,group A3 according to the random number table method,with 50 cases in each group.Group A1 adopted 5 μg/kg Alfentanil combined with Propofol anesthesia,group A2 used 7 μg/kg Alfentanil combined with Propofol anesthesia,group A3 used 9 μg/kg Alfentanil combined with Propofol anesthesia,while group P was anesthetized with Propofol.The hemodynamics[mean arterial pressure(MAP),heart rate(HR)],recovery time,time to reach hospital discharge standard,egg retrieval time,adverse reactions and satisfaction of four groups were compared.Result:At T0,T1,T2,there were no statistically significant differences in MAP and HR levels among the four groups(P>0.05).The recovery time and time to reach hospital discharge standard in group A1,group A2 and group A3 were shorter than those in group P,the incidences of respiratory depression in group A1 and group A2 were lower than those in group P and group A3,the incidences of body movement in group A2 and group A3 were lower than those in group P and group A1,and the satisfaction of group A1,group A2 and group A3 was higher than that in group P,the differences were statistically significant(P<0.05).There were no significant differences in the recovery time,time to reach hospital discharge standard and satisfaction of group A1,group A2 and group A3,the time of egg retrieval,the incidence of nausea and vomiting of four groups,the incidence of respiratory depression between group A1 and group A2,and the incidence of body movement between group A2 and group A3(P>0.05).Conclusion:The anesthesia effect in painless egg retrieval surgery of Alfentanil using 7 μg/kg combined with Propofol is good,and the postoperative recovery quality of patients is good,with high satisfaction,and there is no significant change in patient's hemodynamics,which can reduce the occurrence of adverse reactions.

Painless egg retrieval surgeryDifferent doses of AlfentanilPropofolHemodynamicsSatisfaction

黄姣艳、张媛

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井冈山大学附属医院麻醉科 江西 吉安 343000

井冈山大学附属医院药剂科 江西 吉安 343000

无痛取卵术 不同剂量阿芬太尼 丙泊酚 血流动力学 满意度

江西省卫生健康委科技项目

202310855

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(15)
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