Clinical Significance of Peripheral Blood Leukocyte Classification Counts and Their Proportions in Patients with Influenza A Virus Infection
Objective:To explore the application value of peripheral blood leukocyte classification counts and their proportions in patients with influenza A virus infection.Method:A total of 153 patients with respiratory and related systemic symptoms who were admitted to the Fever Clinic of Fengpu Street Community Health Service Center,Fengxian District,Shanghai from March to April 2023 were retrospective collected,according to the results of rapid antigen test of influenza A virus,they were divided into 71 cases of influenza A group and 82 cases of non influenza A group.The patient's sex,age,maximum body temperature,white blood cell count(WBC),neutrophil count(NC),lymphocyte count(LC),monocyte count(MC),eosinophil count(EOS)and neutrophil percentage(NE%),lymphocyte percentage(LY%),monocyte percentage(MO%),eosinophil percentage(EOS%)were recorded.The diagnostic efficacy of leukocyte classification counts and its proportion for influenza A virus infection was evaluated by the receiver operating characteristics(ROC)curve.Result:WBC,NC,LC,EOS and EOS%in the influenza A group were lower than those in the non influenza A group(P<0.05);and the highest body temperature and MO%were higher than those in the non influenza A group(P<0.05).The ROC analysis results showed that the area under the curve for MO%to diagnose influenza A virus infection was 0.704,the optimal critical point was 9.35%,and the sensitivity and specificity were 77.5%and 65.9%,respectively.Conclusion:The peripheral blood WBC,NC,LC,EOS and EOS%of patients infected with influenza A virus decrease,while the MO%increase,which has good auxiliary diagnostic value for influenza A virus infection.
Influenza A virusWhite blood cell countMonocyte count proportion