首页|鹰潭地区婴幼儿社区获得性肺炎的病原学特征及血清降钙素原、维生素A、维生素D水平分析

鹰潭地区婴幼儿社区获得性肺炎的病原学特征及血清降钙素原、维生素A、维生素D水平分析

扫码查看
目的:分析鹰潭地区婴幼儿社区获得性肺炎的病原学特征及血清降钙素原(PCT)、维生素A、维生素D水平.方法:回顾性纳入 2020 年 6 月—2023 年 6 月贵溪市人民医院收治的 80 例社区获得性肺炎患儿病例资料进行研究.采集所有患儿痰标本,均进行细菌鉴定、病毒检测,分析其病原学特征,依据患儿病情严重程度将其分为重度肺炎组(n=28)与轻度肺炎组(n=52),比较两组患儿的血清PCT、维生素A、维生素D水平.结果:80 例患儿细菌检出阳性 42 例,占比 52.50%,各年龄段患儿均以肺炎链球菌最为常见,共 11 例,占细菌检出阳性的 26.19%,流感嗜血杆菌次之,共 9 例,占细菌检出阳性的 21.43%.80 例患儿病毒检出阳性 49 例,占比 61.25%,其中最常见的病毒病原为呼吸道合胞病毒(RSV),共 26 例,占病毒检出阳性的 53.06%;流感病毒A(IVA)共检出 6 例,占病毒检出阳性的12.24%;副流感病毒 1 型(PIV1)共检出 5 例,占病毒检出阳性的 10.20%.在≤3 岁年龄段患儿中RSV检出率最高(41.67%),其次为PIV1(8.33%);在 4~5 岁年龄段患儿中RSV检出率最高(18.75%),其次为IVA(12.50%).重度肺炎组PCT水平高于轻度肺炎组,差异有统计学意义(P<0.05);重度肺炎组维生素A、25-二羟维生素D3[25-(OH)D3]水平均低于轻度肺炎组,差异均有统计学意义(P<0.05).结论:肺炎链球菌与RSV分别为鹰潭地区婴幼儿社区获得性肺炎的第一细菌病原体与病毒病原体,血清PCT、维生素A、维生素D水平检测可以辅助临床判断社区获得性肺炎患儿病情严重程度.
Etiological Characteristics of Community-acquired Pneumonia and Levels of Serum Procalcitonin,Vitamin A and Vitamin D in Infants in Yingtan
Objective:To analyze etiological characteristics of community-acquired pneumonia and levels of serum procalcitonin(PCT),vitamin A and vitamin D in infants in Yingtan.Method:A retrospective collection was performed on case data of 80 infants with community-acquired pneumonia in Guixi People's Hospital between June 2020 and June 2023.The sputum samples were collected from all infants for bacterial identification and viral test.The etiological characteristics were analyzed.According to disease severity,infants were divided into severe pneumonia group(n=28)and mild pneumonia group(n=52).The levels of serum PCT,vitamin A and vitamin D in the two groups were compared.Result:Among the 80 infants,there were 42 cases(52.50%)with bacteria,mainly on Streptococcus pneumoniae(11 cases,26.19%)and Haemophilus influenzae(9 cases,21.43%).Among the 80 infants,there were 49 cases(61.25%)with viruses,mainly on respiratory syncytial virus(RSV,26 cases,53.06%),influenza virus A(IVA,6 cases,12.24%)and type 1 parainfluenza virus(PIV1,5 cases,10.20%).In infants with age of≤3 years,detection rate of RSV was the highest(41.67%),followed by PIV1(8.33%).In infants with age of 4-5 years,detection rate of RSV was the highest(18.75%),followed by IVA(12.50%).PCT level in severe pneumonia group was higher than that in mild pneumonia group(P<0.05),while levels of vitamin A and 25-(OH)D3 were lower than those in mild pneumonia group(P<0.05).Conclusion:Streptococcus pneumoniae and RSV are the first bacterial pathogen and viral pathogen of community-acquired pneumonia in infants in Yingtan,respectively.Serum PCT,vitamin A and vitamin D can be applied to clinically determine the severity of community-acquired pneumonia.

Community-acquired pneumoniaEtiological characteristicProcalcitoninVitamin AVitamin D

江军浪、揭帮中、杨霞

展开 >

贵溪市人民医院儿科 江西 贵溪 335400

贵溪鸿康医院综合科 江西 贵溪 335400

社区获得性肺炎 病原学特征 降钙素原 维生素A 维生素D

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(15)
  • 12