Effect of Different Flow Rates in HFNC Treatment on the Rehabilitation Process of COPD Patients with Respiratory Failure
Objective:To investigate the effects of different flow rates of high flow nasal cannula(HFNC)on the rehabilitation process of patients with chronic obstructive pulmonary disease(COPD)complicated with respiratory failure.Method:A total of 147 patients with COPD complicated with respiratory failure admitted to Ji'an First People's Hospital from October 2021 to October 2023 were selected and randomly divided into low-speed group(30 L/min),medium-speed group(40 L/min)and high-speed group(50 L/min),with 49 cases in each group.Clinical indicators(tracheal intubation rate,length of hospital stay),blood gas analysis[arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2)],respiratory rate,respiratory comfort[numerical rating scale(NRS)],symptom score and quality of life[COPD assessment test(CAT),St George's respiratory questionnaire(SGRQ)]were compared among the three groups.Result:There was no significant difference in tracheal intubation rate among the three groups(P>0.05).The length of hospital stay in the medium-speed group and the high-speed group were shorter than that in the low-speed group(P<0.05),but there was no statistical significance between the medium-speed group and the high-speed group(P>0.05).After treatment,PaO2 and PaCO2 in the medium-speed group and high-speed group were higher than those in the low-speed group(P<0.05),and there were no statistical significance between the medium-speed group and high-speed group(P>0.05).There was no significant difference in respiratory rate among the three groups after treatment(P>0.05).After treatment,NRS scores in low-speed group and medium-speed group were lower than that in high-speed group(P<0.05),but there was no significant difference in NRS score between low-speed group and medium-speed group(P>0.05).After treatment,CAT scores and SGRQ scores in medium-speed group and high-speed group were lower than those in low-speed group(P<0.05),and there were no statistical significance between medium-speed group and high-speed group(P>0.05).Conclusion:In the treatment of COPD patients with respiratory failure,HFNC at a flow rate of 40 L/min can not only significantly improve blood gas analysis indicators,accelerate recovery,improve exercise endurance and quality of life,but also ensure the comfort of patients.
Chronic obstructive pulmonary diseaseRespiratory failureHigh flow nasal cannulaProcess of rehabilitation
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