Effect of Modified Fangji Huangqi Decoction Combined with Zhenwu Decoction in the Adjuvant Treatment of Refractory Heart Failure
Objective:To explore the clinical effect of modified Fangji Huangqi Decoction combined with Zhenwu Decoction in the adjuvant treatment of patients with refractory heart failure.Method:A total of 86 patients with refractory heart failure treated in Tengzhou Traditional Chinese Medical Hospital from January 2022 to December 2023 were selected and divided into experimental group(n=43)and control group(n=43)by random number table method.Patients in the control group received basic symptomatic treatment,patients in the experimental group added modified Fangji Huangqi Decoction combined with Zhenwu Decoction treatment.The TCM syndromes scores,cardiac function,brain natriuretic peptide(BNP),glutathione peroxidase(GSH-Px)and galactin-3(Gal-3)were compared between the two groups.Result:After treatment,TCM syndromes scores in experimental group were lower than those in control group,the differences were statistically significant(P<0.05).After treatment,left ventricular ejection fraction(LVEF)of experimental group was higher than that of control group,and left ventricular end-systolic diameter(LVESD)and left ventricular end-diastolic diameter(LVEDD)of experimental group were smaller than those of control group,the differences were statistically significant(P<0.05).After treatment,the levels of BNP and Gal-3 in experimental groups were lower than those in control group,and the level of GSH-Px was higher than that in control group,the differences were statistically significant(P<0.05).Conclusion:The effect of basic symptomatic treatment for patients with refractory heart failure is not ideal,the patient's condition is still progressive,using modified Fangji Huangqi Decoction combined with Zhenwu Decoction adjuvant treatment can control the disease progression.
Refractory heart failureFangji Huangqi Decoction combined with Zhenwu DecoctionSpirolactone
万方数据
维普
