Clinical Effect of Tanreqing Injection Combined with Levofloxacin in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated with Pneumonia
Objective:To explore the clinical effect of Tanreqing Injection combined with Levofloxacin in the treatment of acute exacerbation of chronic obstructive pulmonary disease(COPD)complicated with pneumonia.Method:A total of 104 patients with acute exacerbation of COPD complicated with pneumonia admitted to Binzhou Central Hospital from July 2022 to June 2023 were selected and divided into study group(n=52)and control group(n=52)by random number table method.The control group was treated with Levofloxacin,and the study group was treated with Tanreqing Injection combined with Levofloxacin.The clinical efficacy,inflammatory factors and blood gas indexes were compared between the two groups.Result:The total effective rate of the study group(92.31%)was higher than that of the control group(76.92%),the difference was statistically significant(P<0.05).After treatment,C reactive protein(CRP)and procalcitonin(PCT)levels were decreased in both groups,and those in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,arterial partial pressure of carbon dioxide(PaCO2)decreased and arterial partial pressure of oxygen(PaO2)increased in both groups,PaCO2 in the study group was lower than that in the control group,and PaO2 was higher than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Tanreqing Injection combined with Levofloxacin in the treatment of acute exacerbation of COPD complicated with pneumonia can improve clinical efficacy,relieve inflammatory reaction and improve blood gas indexes.
Tanreqing InjectionLevofloxacinAcute exacerbation of chronic obstructive pulmonary diseasePneumonia
万方数据
维普
