中国医学创新2024，Vol.21Issue(21) ：110-114.DOI:10.3969/j.issn.1674-4985.2024.21.027

超声引导下注射富血小板血浆联合中药熏洗对早期膝骨关节炎患者的影响

Effect of Ultrasound-guided Injection of Platelet-rich Plasma Combined with Traditional Chinese Medicine Fumigation on Patients with Early Knee Osteoarthritis

夏奇 罗萍 刘名峰 林嘉敏
中国医学创新2024，Vol.21Issue(21) ：110-114.DOI:10.3969/j.issn.1674-4985.2024.21.027
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超声引导下注射富血小板血浆联合中药熏洗对早期膝骨关节炎患者的影响

Effect of Ultrasound-guided Injection of Platelet-rich Plasma Combined with Traditional Chinese Medicine Fumigation on Patients with Early Knee Osteoarthritis

夏奇 1罗萍 2刘名峰 2林嘉敏1
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作者信息

  • 1. 佛山市三水区人民医院康复科 广东 佛山 528100
  • 2. 佛山市三水区人民医院中医临床科 广东 佛山 528100
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摘要

目的:探讨超声引导下注射富血小板血浆联合中药熏洗对早期膝骨关节炎患者的影响.方法:选取 2022 年 1 月—2023 年 12 月佛山市三水区人民医院收治的 86 例早期膝骨关节炎患者作为研究对象,随机分为常规组(接受中药熏洗治疗)与联合组(接受超声引导下注射富血小板血浆联合中药熏洗治疗),各 43 例.对比两组临床疗效、疼痛介质、血清炎症因子水平及膝关节功能.结果:联合组总有效率为 95.35%,高于常规组的 81.40%,差异有统计学意义(P<0.05).干预后,联合组应激蛋白(SP)、多巴胺(DA)、前列腺素E2(PGE2)、5-羟色胺(5-HT)水平均低于常规组,差异均有统计学意义(P<0.05).干预后,联合组白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)水平均低于常规组,差异均有统计学意义(P<0.05).干预后,联合组疼痛、功能障碍评分均低于常规组,差异均有统计学意义(P<0.05).结论:超声引导下注射富血小板血浆联合中药熏洗可以显著提高早期膝骨关节炎患者的疗效,减轻疼痛,降低炎症介质水平,改善膝关节功能.

Abstract

Objective:To investigate the effects of ultrasound-guided injection of platelet-rich plasma combined with traditional Chinese medicine fumigation on patients with early knee osteoarthritis.Method:A total of 86 patients with early knee osteoarthritis treated in Foshan Sanshui District People's Hospital from January 2022 to December 2023 were selected as the study subjects,and they were randomly divided into conventional group(receiving traditional Chinese medicine fumigation treatment)and combined group(receiving ultrasound-guided injection of platelet-rich plasma combined with traditional Chinese medicine fumigation treatment),with 43 cases in each group.The clinical efficacy,pain mediators,levels of serum inflammatory factors and knee function were compared between the two groups.Result:The total effective rate of combined group was 95.35%,which was higher than 81.40%of conventional group,the difference was statistically significant(P<0.05).After intervention,the levels of stress protein(SP),dopamine(DA),prostaglandin E2(PGE2)and 5-hydroxytryptamine(5-HT)in combined group were lower than those in conventional group,the differences were statistically significant(P<0.05).After intervention,the levels of interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)in combined group were lower than those in conventional group,the differences were statistically significant(P<0.05).After intervention,the pain and dysfunction scores of the combined group were lower than those of the conventional group,the differences were statistically significant(P<0.05).Conclusion:Ultrasound-guided injection of platelet-rich plasma combined with traditional Chinese medicine fumigation can significantly improve the curative effect of early knee osteoarthritis patients,reduce pain,reduce the levels of inflammatory mediators,and improve knee joint function.

关键词

超声引导下注射富血小板血浆/早期膝骨关节炎/中药熏洗/疼痛介质水平

Key words

Ultrasound-guided injection of platelet-rich plasma/Early knee osteoarthritis/Traditional Chinese medicine fumigation/Pain mediators level

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出版年

2024
中国医学创新
中国保健协会

中国医学创新

影响因子：1.706
ISSN：1674-4985
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