首页|PCT、NLR、N/LPR对重症急性胰腺炎并发急性肾损伤的预测价值

PCT、NLR、N/LPR对重症急性胰腺炎并发急性肾损伤的预测价值

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目的:分析血降钙素原(PCT)、中性粒细胞/淋巴细胞比值(NLR)、中性粒细胞/淋巴细胞和血小板比值(N/LPR)对重症急性胰腺炎(SAP)并发急性肾损伤(AKI)的预测价值.方法:选取2020年2 月—2023 年 8 月在吉安市中心人民医院进行治疗的 130 例SAP患者,根据是否并发AKI将其分为AKI组(n=28)、非AKI组(n=102).入院时,比较两组的临床资料及实验室指标,采用logistic回归分析SAP患者并发AKI的影响因素,采用受试者操作特征(ROC)曲线分析实验室相关指标对SAP并发AKI的预测价值.结果:AKI组C反应蛋白(CRP)、PCT、NLR、N/LPR及乳酸水平均高于非AKI组,白蛋白水平低于非AKI组,差异均有统计学意义(P<0.05);logistic回归分析显示,PCT、NLR及N/LPR升高是SAP患者并发AKI的危险影响(P<0.05);ROC曲线结果显示,PCT、NLR、N/LPR的AUC值分别为 0.794、0.747 及 0.897.结论:PCT、NLR、N/LPR是SAP患者发生AKI的影响因素,且早期预测价值较高,为AKI早期预防并及时干预提供依据.
Prognostic Value of PCT,NLR and N/LPR in Patients with Severe Acute Pancreatitis Concurrent Acute Kidney Injury
Objective:To analyze the predictive value of procalcitonin(PCT),neutrophil/lymphocyte ratio(NLR),neutrophil/lymphocyte and platelet ratio(N/LPR)of severe acute pancreatitis(SAP)concurrent acute kidney injury(AKI).Method:A total of 130 SAP patients treated in Ji'an Central People's Hospital from February 2020 to August 2023 were selected and divided into AKI group(n=28)and non-AKI group(n=102)according to whether they had concurrent AKI.At admission to hospital,the clinical data and laboratory indicators of the two groups were compared,the influencing factors of SAP patients with concurrent AKI were analyzed by logistic regression,and the predictive value of laboratory-related indicators on SAP concurrent AKI was analyzed by receiver operating characteristics(ROC)curve.Result:The levels of C reactive protein(CRP),PCT,NLR,N/LPR and lactic acid in AKI group were higher than those in non-AKI group,while the albumin level was lower than that in non-AKI group,the differences were statistically significant(P<0.05).logistic regression analysis showed that increased PCT,NLR and N/LPR were the risk factors for AKI in SAP patients(P<0.05).ROC curve results showed that the AUC values of PCT,NLR and N/LPR were 0.794,0.747 and 0.897,respectively.Conclusion:PCT,NLR and N/LPR are the influential factors for AKI in SAP patients,and the early prediction value are high,which provide a basis for early prevention and timely intervention of AKI.

Severe acute pancreatitisAcute kidney injuryPredictive value

周艺敏、夏国盛

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吉安市中心人民医院消化科 江西 吉安 343000

重症急性胰腺炎 急性肾损伤 预测价值

吉安市指导性科技计划项目

20233-043403

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(21)