The Application Value of Radiofrequency Catheter Ablation and Left Atrial Appendage Occlusion in the Treatment of Elderly Patients with Atrial Fibrillation
Objective:To investigate the therapeutic effect of radiofrequency catheter ablation and left atrial appendage occlusion in elderly patients with atrial fibrillation(AF).Method:A total of 86 elderly AF patients admitted to the People's Hospital of Qiannan from May 2020 to May 2023 were selected,and were divided into two groups by random number table method,with 43 cases in each group.The control group underwent radiofrequency catheter ablation,and the observation group added left atrial appendage occlusion.The atrial rate changes,cardiac function indicators,serological indicators,coagulation function,quality of life,embolic events and bleeding events were compared between the two groups.Result:At 3 months after surgery,the atrial rate in the observation group was(70.52±6.32)beats/min,which was lower than(78.54±6.74)beats/min in the control group,the left atrial diameter(LAD)and left ventricular end diastolic diameter(LVEDD)were(31.74±3.15)mm and(41.02±4.13)mm,which were shorter than(34.69±3.23)mm and(45.69±4.22)mm in the control group,the left ventricular ejection fraction(LVEF)was(58.96±5.74)%,which was higher than(53.67±5.48)%in the control group,the differences were statistically significant(P<0.05).At 3 months after surgery,the levels of D-dimer(D-D)and N-terminal-type B natriuretic peptide precursor(NT-proBNP)were(124.73±10.41)ng/mL and(812.74±85.43)pg/mL,which were lower than(140.85±12.53)ng/mL and(906.62±91.52)pg/mL in the control group,the differences were statistically significant(P<0.05).At 3 months after surgery,the activated partial thromboplastin time(APTT),prothrombin time(PT),and thrombin time(TT)of the observation group were(35.65±3.25)s,(13.12±1.25)s,and(20.49±1.75)s,which were longer than(31.72±3.12)s,(12.25±1.16)s,and(17.52±1.48)s in the control group,the fibrinogen(FIB)was(2.33±0.32)g/L,which was lower than(2.85±0.34)g/L in the control group,the differences were statistically significant(P<0.05).At 3 months after surgery,the quality of life scores in various areas of the observation group were(86.57±5.47)points,(85.74±5.32)points,(88.63±5.24)points,and(89.63±5.18)points,which were higher than(80.13±5.35)points,(79.65±5.27)points,(81.69±5.15)points,and(82.04±5.22)points of the control group,the differences were statistically significant(P<0.05).The incidences of embolic events and bleeding events in the observation group were lower than those in the control group(P<0.05).Conclusion:Combined with radiofrequency catheter ablation and left atrial appendage occlusion can improve the treatment effect of elderly AF,stabilize atrial rate level,accelerate cardiac function recovery,improve coagulation function,and reduce the risk of embolic events and bleeding events.
Atrial fibrillationRadiofrequency catheter ablationLeft atrial appendage occlusionCardiac functionQuality of life
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