Efficacy and Safety of Warming Needle Moxibustion in the Treatment of Chemotherapy-induced Peripheral Neuropathy
Objective:To explore the efficacy and safety of warming needle moxibustion in the treatment of chemotherapy-induced peripheral neuropathy(CIPN).Method:A total of 100 patients with breast cancer CIPN admitted to Nanchang People's Hospital from July 2020 to August 2022 were divided into two groups by random number table method,with 50 cases in each group.The control group was treated with warming needle moxibustion,and the experimental group was treated with acupuncture,both of which were treated for 2 courses.Efficacy and safety,KPS score and quality of life score were compared between the two groups.Result:The total effective rate of experimental group was 94.00%,which was higher than 76.00%of control group,the difference was statistically significant(P<0.05).Compared with control group,KPS score of experimental group after treatment was higher,the difference was statistically significant(P<0.05).After treatment,KPS scores in both groups were higher than those before treatment,the differences were statistically significant(P<0.05).Compared with control group,each item scores of quality of life in experimental groups after treatment were higher,the differences were statistically significant(P<0.05).After treatment,the scores of social function,physical function,cognitive function,emotional function and role function of the two groups were higher than those before treatment,the differences were statistically significant(P<0.05).Compared with the control group,the neurotoxicity of experimental group was less,the difference was statistically significant(P<0.05).Conclusion:Acupuncture has achieved ideal results in the treatment of patients with breast cancer CIPN,which can effectively improve the functional status of patients,improve the quality of life of patients,and reduce the neurotoxicity of chemotherapy drugs.
Chemotherapy-induced peripheral neuropathyWarming needle moxibustionMecobalaminQuality of lifeNeurotoxicity