Clinical Effect of Intensive Atorvastatin Calcium in the Adjuvant Treatment of Senile Coronary Heart Disease Complicated with Heart Failure and Its Influence on the Levels of Interleukin-6 and Serum Amyloid A Protein
Objective:To investigate the effect of intensive Atorvastatin Calcium in the adjuvant treatment of in elderly patients with coronary heart disease complicated with heart failure.Method:A total of 110 elderly patients with coronary heart disease complicated with heart failure admitted to Yingtan People's Hospital from January 2021 to December 2023 were randomly divided into two groups.The control group(n=55)was treated with conventional dose of Atorvastatin Calcium,and the study group(n=55)was treated with intensive Atorvastatin Calcium.Blood lipid levels,cardiac function,inflammatory reaction and adverse reactions were compared between the two groups.Result:After treatment,the levels of triglyceride,total cholesterol,low-density lipoprotein cholesterol,N-terminal pro-brain natriuretic peptide,interleukin-6,tumor necrosis factor-α,serum amyloid A protein and hypersensitive C reactive protein in the study group were lower than those in the control group,and the high-density lipoprotein cholesterol,left ventricular ejection fraction,heart index and stroke volume were higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Intensive Atorvastatin Calcium adjuvant treatment can effectively reduce the levels of inflammatory factors such as serum amyloid A protein and interleukin-6 in elderly patients with with coronary heart disease complicated with heart failure,and improve the cardiac function of patients,with high safety.
Coronary heart diseaseHeart failureAtorvastatin CalciumInterleukin-6Serum amyloid A protein
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维普
