Analysis of Nutritional Risk and Nutrition-related Hematological Indexes in Patients with Stage Ⅳ Non-small Cell Lung Carcer
Objective:To investigate the occurrence of nutritional risk and the changes of nutrition-related hematological indexes in patients with stage Ⅳ non-small cell lung cancer,and to provide a basis for nutritional support through indexes analysis.Method:Clinical data of 92 patients with stage Ⅳ non-small cell lung cancer diagnosed for the first time in Department of Oncology,the Second Hospital of Anhui Medical University from January 2020 to January 2023 were collected retrospectively,including age,gender,body mass index(BMI),utritional risk screening 2002(NRS 2002)score and hematological indexes.The patients were divided into old group(aged 66 to 89)and young and middle-aged group(aged 18 to 65)according to age,and the occurrence of malnutrition and abnormal hematological indexes in the two groups were analyzed.Result:The incidence of nutritional risk in 92 patients with stage Ⅳ non-small cell lung cancer was 22.83%.The incidence of nutritional risk in patients aged 66 to 89 was significantly higher than that in patients aged 18 to 65,the difference was statistically significant(χ2=8.573,P=0.003).The incidence of undernutrition in patients with stage Ⅳ non-small cell lung cancer was 13.04%(12/92).The incidence of undernutrition in the old group(21.57%)was significantly higher than that in the young and middle-aged group(2.44%),the difference was statistically significant(P=0.007).Patients with stage Ⅳ non-small cell lung cancer had a high abnormal rate of blood indexes,and more than 25%of patients had abnormal albumin(ALB),hemoglobin(Hb),white blood cell(WBC)count,absolute lymphocyte value(LYM).The abnormal rates of albumin(ALB),potassium(K)and magnesium(Mg)in the old group were significantly higher than those in the young and middle-aged group,the abnormal rate of WBC was lower than that of the young and middle-aged group,the differences were statistically significant(P<0.05).Conclusion:Patients with stage Ⅳ non-small cell lung cancer have higher nutritional risk,and their nutrition-related hematological indexes are significantly abnormal.