Application of Temperature-sensitive Gel Based on Poloxamer in Local Drug Delivery Systems
Temperature-sensitive in situ gels have attracted wide clinical attention because of their ability to undergo phase transformation according to temperature changes.It is a liquid at room temperature and can quickly form a gel when it is close to human body temperature,so it has the characteristics of easy administration and sustained release of drugs.In recent years,there have been more and more researches on temperature-sensitive gels as a local drug delivery system,among which temperature-sensitive gels based on Poloxamer account for the majority due to their good biocompatibility and non-toxicity.This paper mainly introduces the development and application of temperature-sensitive gel based on Poloxamer in local drug delivery system.
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维普
