Clinical Study on Fluid Resuscitation in Patients with Septic Shock Guided by Mixed Central Veno-arterial Carbon Dioxide Differential Pressure Combined with Inferior Vena Cava Diameter
Objective:To investigate the clinical effect of mixed cantral veno-arterial carbon dioxide differential pressure(Pcv-aCO2)combined with inferior vena cava diameter(IVCD)on fluid resuscitation in patients with septic shock(SS).Method:A total of 83 SS patients admitted to Xinyu People's Hospital from January 2022 to June 2023 were selected and divided into control group(n=42)and observation group(n=41)according to random number table method.The control group received 3 h liquid resuscitation,and the observation group received liquid resuscitation under the guidance of Pcv-aCO2 combined with IVCD.The indexes related to resuscitation,6 h resuscitation standard rate and lactic acid clearance rate,total fluid intake at 6 h and 24 h after resuscitation,mechanical ventilation time and incidence of acute pulmonary edema between the two groups were compared.Result:At 6 h and 24 h after resuscitation,central venous pressure(CVP),mean arterial pressure(MAP)and central venous oxygen saturation(ScvO2)in observation group were higher than those in control group,and lactic acid(Lac)were lower than those in control group,the differences were statistically significant(P<0.05).The 6 h resuscitation standard rate and lactic acid clearance rate in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).At 6 h and 24 h after resuscitation,the total fluid intake in the observation group were less than those in the control group,the differences were statistically significant(P<0.05).The mechanical ventilation time of the observation group was shorter than that of the control group,and the incidence of acute pulmonary edema was lower than that of the control group,the differences were statistically significant(P<0.05).Conclusion:Pcv-aCO2 combined with IVCD can improve the standard rate of resuscitation,reduce the total fluid intake,shorten the mechanical ventilation time,and reduce the incidence of acute pulmonary edema in SS patients.
万方数据
维普
