Application Effects of Cipepofol Alone and Combined with Sufentanil in Painless Gastroscopy Examination of Obese Patients
Objective:To observe the application effects of Cipepofol alone and combined with Sufentanil in painless gastroscopy examination of obese patients.Method:A total of 80 obese patients who underwent painless gastroscopy examination in Nanchang Hongdu Hospital of TCM from January 2022 to September 2023 were selected as the study subjects,they were divided into the control group and the observation group by the random number table method,with 40 patients in each group.The control group was treated with Cipepofol alone,and the observation group was treated with Sufentanil on the basis of the control group.Anesthesia quality,anesthesia related indicators(onset time of anesthesia,awakening time,orientation recovery time and total dosage of Cipepofol),vital signs[heart rate(HR),mean arterial pressure(MAP)and oxygen saturation of blood(SpO2)],and incidence of adverse reactions(hypotension,respiratory depression,body movement,nausea and vomiting,and injection pain)in two groups were compared.Result:The excellent and good rate of anesthesia in the observation group(97.50%)was higher than that in the control group(80.00%),the difference was statistically significant(P<0.05).The onset time of anesthesia,awakening time,orientation recovery time in the observation group were earlier than those in the control group,and total Cipepofol dosage was less than that in the control group,the differences were statistically significant(P<0.05).Before anesthesia,there were no statistically significant differences in HR,MAP and SpO2 between the two groups(P>0.05);HR,MAP and SpO2 in the observation group were higher than those in the control group when inserting and removing the gastroscope,the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group(5.00%)was lower than that in the control group(25.00%),the difference was statistically significant(P<0.05).Conclusion:Applying Cipepofol combined with Sufentanil in painless gastroscopy examination of obese patients compared with Cipepofol alone,can achieve better anesthetic effect,faster onset of anesthesia,shorter time for respiration recovery and shorter awakening time after examination,less use of anesthetic drugs,and more stable vital signs during examination,with a lower incidence of adverse reactions.
万方数据
维普
