Early Diagnostic Value of LDH,NT-proBNP and ALB Levels in Incomplete Kawasaki Disease
Objective:To explore the early diagnostic value of lactate dehydrogenase(LDH),N-terminal pro-brain natriuretic peptide(NT-proBNP),albumin(ALB)levels in incomplete Kawasaki disease(IKD).Method:A total of 80 children with IKD treated in Bayannur Hospital from January 2020 to January 2023 were selected as IKD group,and 80 children with typical Kawasaki disease(KD)treated in our hospital during the same period were selected as KD group.LDH,NT-proBNP and ALB levels of all children were detected after admission,and the general situation and LDH,NT-proBNP and ALB levels of IKD group and KD group were compared.The early diagnostic value of LDH,NT-proBNP and ALB levels in IKD were analyzed by receiver operator characteristic(ROC)curve.At the same time,80 children with IKD were divided into two subgroups according to the status of coronary artery injury,namely the non-injury group(n=30)and the injury group(n=50),and the levels of LDH,NT-proBNP and ALB were compared between the two groups.Result:There were no significant differences in gender,age and the proportion of high fever,pleomorphic exanthem and oral mucosal changes between IKD group and KD group(P>0.05).The fever time in IKD group was longer than that in KD group,and the proportion of finger tip changes,conjunctival congestion and cervical lymph node tumefaction were lower than those in KD group,the differences were statistically significant(P<0.05).The levels of LDH,NT-proBNP and ALB in IKD group were significantly higher than those in KD group,the differences were statistically significant(P<0.05).The diagnostic efficiency of LDH,NT-proBNP and ALB in combination was better than that of single detection,the levels of LDH,NT-proBNP and ALB in the injury group were significantly higher than those in the non-injury group,the differences were statistically significant(P<0.05).Conclusion:LDH,NT-proBNP and ALB levels have a high value in the early diagnosis of IKD,and the combination of LDH,NT-proBNP and ALB can be considered to diagnose IKD.
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