Maxillofacial space infection is a general term for inflammation in the oral cavity,maxillofacial and neck potential spaces,and is one of the common oral emergencies,which can cause intracranial infection or mediastinitis in severe cases.Due to the increase in antibiotic resistance,rapid and effective identification of pathogenic bacteria is needed in clinic.The development of next-generation sequencing technology provides a new detection method for identifying pathogenic bacteria in early clinical stage,so as to timely understand the distribution characteristics of pathogenic bacteria,determine the types of antibiotics,and target application,in order to obtain good treatment results.In this paper,the characteristics and drug resistance of pathogens associated with oral and maxillofacial space infection were summarized,aiming at formulating reasonable and effective personalized medication protocols,and providing references for clinical research and experimental drug use.
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