Analysis of Influencing Factors of IVF-ET Assisted Pregnancy Outcomes in PCOS Patients
Objective:To analyze the influencing factors of in vitro fertilization-embryo transfer(IVF-ET)assisted pregnancy outcomes in patients with polycystic ovary syndrome(PCOS).Method:A total of 91 PCOS patients who underwent IVF-ET assisted pregnancy in Ganzhou Maternal and Child Health Hospital from January 2021 to December 2022 were selected,followed up for 6 months,and their assisted pregnancy outcomes(clinical pregnancy rate and non-pregnancy rate)were analyzed.The levels of anti-miller tube hormone(AMH),progesterone(P),prolactin(PRL),luteinizing hormone(LH),testosterone(T),estradiol(E2)and follicle stimulating hormone(FSH)in patients with different clinical characteristics and different assisted pregnancy outcomes were compared,and the influencing factors of clinical pregnancy in PCOS patients were analyzed by logistic regression.Result:Among the 91 PCOS patients,68 were clinically pregnant and 23 were not pregnant.There were no significant differences in the levels of P,PRL,LH,T,age and PCOS course between clinically pregnant and non-pregnant patients(P>0.05).Body mass index(BMI)of clinically pregnant patients was lower than that of non-pregnant patients,and serum AMH,E2 and FSH levels were higher than those of non-pregnant patients,the differences were statistically significant(P<0.05).Multiple logistic regression analysis showed that the decreased levels of AMH,E2 and FSH were risk factors for clinical pregnancy in PCOS patients(P<0.05).Conclusion:Elevated levels of AMH,E2 and FSH are protective factors affecting clinical pregnancy in PCOS patients,and clinical pregnancy can be predicted by serum AMH,E2 and FSH levels during pregnancy.
Polycystic ovary syndromeIn vitro fertilization-embryo transferLevel of sex hormone