Research Progress in the Mechanism of Epithelial-mesenchymal Transition Influencing the Invasion and Metastasis of Neuroblastoma
Neuroblastoma(NB)is one of the common malignant tumors with high heterogeneity,rapid growth,and easy metastasis in children.Epithelial-mesenchymal transition(EMT)is an important process in the invasion and metastasis of malignant tumor cells.In recent years,more and more studies have shown that traditional Chinese medicine has a significant inhibitory effect on the EMT process of malignant tumor cells.This article reviews the progress in signaling pathways related to EMT,the influence and mechanism of traditional Chinese medicine on EMT in malignant tumor cells,and the relationship between EMT and NB invasion and metastasis.
NeuroblastomaEpithelial-mesenchymal transitionTraditional Chinese medicineInvasionMetastasis
国家科技期刊平台
NSTL
万方数据
