Application of Ultrasound-guided Thoracic Nerve Block in Anesthesia for Radical Mastectomy
Objective:To evaluate the anesthetic efficacy of ultrasound-guided thoracic nerve block in radical mastectomy and its influence on postoperative pain control.Method:A total of one hundred patients undergoing radical mastectomy at Binzhou Medical University Hospital from September 2022 to June 2023 were selected as the subjects of this study,patients were divided into a control group(n=50)and an observation group(n=50)by random number table method.The control group received conventional general anesthesia,observation group received ultrasound-guided thoracic nerve block on the basis of the control group.Anesthesia and awakening period quality(time for tracheal tube removal,autonomous breathing recovery time,awakening time,and recovery room retention time),postoperative analgesic effects at 6,12,24,and 48 hours[visual analogue scale(VAS),effective pain relief duration],oxidative stress levels at different time points[preanesthetic,end of surgery,24 hours postoperatively,48 hours postoperatively serum malondialdehyde(MDA),superoxide dismutase(SOD)]and incidence of adverse reactions(nausea,vomiting,postoperative chills,bradycardia,dizziness)were compared between two groups.Result:Times for tracheal tube removal,autonomous breathing recovery,awakening in the observation group were earlier than those in the control group,and recovery room stay in the observation group was significantly shorter than that in the control group,the differences were statistically significant(P<0.05).The VAS scores at 6,12,24,and 48 hours postoperatively in the observation group were significantly lower than those in the control group,duration of effective pain relief was longer than that in the control group,the differences were statistically significant(P<0.05).At the end of surgery,and at 24 and 48 hours postoperatively,the serum MDA levels in both groups were higher than before anesthesia induction(P<0.05);at 24 and 48 hours postoperatively,the serum MDA levels in the observation group were lower than those in the control group,while the SOD levels were higher than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between two groups(P>0.05).Conclusion:Ultrasound-guided thoracic nerve block on the basis of general anesthesia significantly improves anesthesia quality and postoperative pain relief in patients undergoing radical mastectomy,reduces recovery time,decreases oxidative stress levels,and does not increase the incidence of adverse reactions.
万方数据
维普
