Effect of Huatan Dingxuan Formula Combined with Betahistine Hydrochloride Tablets in the Treatment of Senile Vertigo and Its Influence on Cerebral Blood Flow Velocity
Objective:To investigate the clinical effect of Huatan Dingxuan Formula combined with Betahistine Hydrochloride Tablets in the treatment of senile vertigo and its influence on cerebral blood flow velocity.Method:A total of 80 senile vertigo patients admitted to Department of Brain Disease,Yangjiang Hospital of Traditional Chinese Medicine from April 2022 to April 2024 were divided into control group and experimental group by random number table method,with 40 cases in each group.The control group was given conventional treatment(symptomatic treatment and oral Betahistine Hydrochloride Tablets),and the experimental group was given Huatan Dingxuan Formula on the basis of the control group,the course of treatment was 1 month.The efficacy,safety,symptoms integrals,cerebral blood flow velocity and hemorheology before and after treatment were compared between the two group.Result:The total effective rate of experimental group was higher than that of control group,the difference was statistically significant(P<0.05).There was no significant difference in the symptoms integrals before treatment between the two groups(P>0.05);after treatment,the syndromes integrals of experimental group was lower than that of control group(P<0.05).There were no significant differences in cerebral blood flow velocity between the two groups(P>0.05);after treatment,the blood flow velocity of left and right vertebral artery and basilar artery in experimental group were higher than those in control group(P<0.05).There were no significant differences in hemorheology indexes between the two groups before treatment(P>0.05);after treatment,plasma viscosity,hematocrit and whole blood high tangential viscosity of experimental group were lower than those of control group(P<0.05).No serious adverse reactions occurred in both groups.Conclusion:Huatan Dingxuan Formula combined with Betahistine Hydrochloride Tablets has a positive effect in the treatment of senile vertigo,which can significantly improve the symptoms integrals,cerebral blood flow velocity and hemorheology of patients.
万方数据
维普
