Impact of Microwave Ablation and Traditional Open Thyroid Surgery on Menopausal Patients with Benign Thyroid Nodules
Objective:To explore the effect of microwave ablation and traditional open thyroid surgery on benign thyroid nodule in menopause.Method:A total of 168 menopausal patients with benign thyroid nodules admitted to the Third People's Hospital of Jiujiang City from January 2019 to October 2022 were selected as the study objects,and they were divided into control group and study group according to the surgical method,with 84 cases in each group.The control group was treated with traditional open thyroid surgery,and the study group was treated with microwave ablation.The levels of serum free triiodothyronine(FT3),serum free thyroxine(FT4),thyroid stimulating hormone(TSH),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and C reactive protein(CRP)were compared between the two groups.The levels of CD4+and CD8+were detected,and the ratio of CD4+/CD8+was calculated.The surgery conditions,treatment effect,complication rate and recurrence rate were compared between the two groups.Result:The blood loss and postoperative drainage volume of the study group were lower than those of the control group,and the surgery time and incision length were shorter than those of the control group(P<0.05).One month after surgery,FT3,FT4 levels in two groups were lower than those before surgery,TSH levels were higher than those before surgery,and FT3,FT4 and TSH levels in the study group were higher than those in the control group(P<0.05).On the first day after surgery,IL-6,TNF-α and CRP in both groups were higher than those before surgery,but those in the study group were lower than those in the control group(P<0.05).On the first day after surgery,CD4+and CD4+/CD8+in both groups were lower than those before surgery,and CD8+were higher than those before surgery,but the levels of CD4+and CD4+/CD8+in the observation group were higher than those in the control group,and the level of CD8+was lower than that in the control group(P<0.05).The total effective rate of the study group was higher than that of the control group,and the complication rate and recurrence rate were lower than those of the control group(P<0.05).Conclusion:Microwave ablation can effectively improve the perioperative conditions related to menopausal patients with benign thyroid nodules,with minimal impact on thyroid function,the procedure also has a low rate of complications and recurrence,and the prognosis is favorable.
Microwave ablationTraditional open thyroid surgeryBenign thyroid nodulePrognosisRecurrence
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