Effect of Sodium Zirconium Cyclosilicate on Blood Potassium Level,Adverse Reactions and Clinical Efficacy in Maintenance Hemodialysis Patients
Objective:To investigate the effect of Sodium Zirconium Cyclosilicate on blood potassium levels,adverse reactions,and clinical efficacy in maintenance hemodialysis(MHD)patients.Method:A total of 100 MHD patients admitted to Yangzhou Second People's Hospital from October 2021 to October 2023 were selected,and were divided into control group and observation group by random number table method,with 50 cases in each group.Both groups were treated with conventional MHD,while the control group was treated with low potassium diet,health education,basic blood pressure reduction,correction of anemia and abnormal metabolism of calcium and phosphorus.The observation group received Sodium Zirconium Cyclosilicate treatment on the basis of the control group's treatment.Blood potassium related indicators(blood potassium,blood calcium,blood sodium,blood magnesium,blood phosphorus),incidence of adverse reactions and clinical efficacy were compared between two groups.Result:There were no significant differences in blood calcium,blood sodium,blood magnesium,and blood phosphorus levels between the two groups before and after treatment(P>0.05);after treatment,the blood potassium level in the observation group was lower than that before treatment and significantly lower than that in the control group(P<0.05).The incidence of adverse reactions in the observation group was 4.00%and 2.00%in the control group,there was no significant difference between the two groups(P>0.05).The total effective rate of the observation group was 98.00%,while that of the control group was 84.00%,that in observation group was higher than that in the control group(P<0.05).Conclusion:Sodium Zirconate Cyclosilicate can reduce blood potassium levels in MHD patients,without causing electrolyte disorders in the body,it has good clinical efficacy and a low incidence of adverse reactions.
万方数据
维普
