Prognosis and Influencing Factors of Ultrasound-guided Microwave Ablation in the Treatment of Papillary Thyroid Carcinoma
Objective:To investigate the prognosis and influencing factors of ultrasound-guided microwave ablation for papillary thyroid carcinoma.Method:The medical records of 132 patients with papillary thyroid carcinoma admitted to Shangrao Municipal Hospital from April 2018 to April 2020 were selected for retrospective analysis.All patients underwent microwave ablation under ultrasound guidance.The medical records of all enrolled patients were collected and organized,and outpatient follow-up data within 3 years were collected.Based on whether lymph node metastasis or recurrence was detected during the follow-up period,the patients were divided into the recurrence/metastasis group and the non-recurrence/non-metastasis group.The related factors affecting the recurrence and metastasis of papillary thyroid carcinoma after ablation were analyzed by logistic regression.Result:Among 132 patients with papillary thyroid carcinoma,26 cases(19.70%)had recurrence/metastasis,and 106 cases(80.30%)had non-recurrence/non-metastasis.The proportion of male,multiple lesions,maximum diameter of tumor≥10 mm,and close to the capsule in the recurrence/metastasis group were higher than those in the non-recurrence/non-metastasis group,the differences were statistically significant(P<0.05).The results of logistic regression analysis showed that male[OR=3.356,95%CI(1.006,11.189)],multiple lesions[OR=18.435,95%CI(3.919,86.715)],maximum tumor diameter≥10 mm[OR=88.053,95%CI(10.965,707.112)],and close to the capsule[OR=52.081,95%CI(9.975,271.929)]were risk factor for recurrence/metastasis of papillary thyroid carcinoma after ablation(P<0.05).Conclusion:The recurrence and metastasis rate of papillary thyroid cancer after ablation therapy is relatively high,and male patients,multiple lesions,increased tumor diameter,and tight adherence to the capsule are related to ultrasound-guided microwave ablation therapy for postoperative recurrence and metastasis of papillary thyroid cancer.