首页|超声引导下微波消融治疗甲状腺乳头状癌的预后及影响因素

超声引导下微波消融治疗甲状腺乳头状癌的预后及影响因素

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目的:探究超声引导下微波消融治疗甲状腺乳头状癌的预后及影响因素.方法:选取2018年4 月—2020 年 4 月上饶市立医院收治的 132 例甲状腺乳头状癌患者的病历资料进行回顾性分析,所有患者均行超声引导下微波消融治疗,收集并整理所有入组患者病历资料,收集患者 3 年内门诊复查资料,根据患者复查期间是否监测到淋巴结转移或复发为依据,分为复发转移组和非复发转移组.logistic逐步回归分析影响甲状腺乳头状癌消融治疗后复发转移的相关因素.结果:132例甲状腺乳头状癌患者中复发转移26例(19.70%),非复发转移106例(80.30%).复发转移组中男性、病灶多发、肿瘤最大径≥10 mm、紧贴包膜所占比例均高于非复发转移组,差异均有统计学意义(P<0.05).logistic逐步回归分析结果显示,男[OR=3.356,95%CI(1.006,11.189)]、病灶多发[OR=18.435,95%CI(3.919,86.715)]、肿瘤最大径≥10 mm[OR=88.053,95%CI(10.965,707.112)]、紧贴包膜[OR=52.081,95%CI(9.975,271.929)]均是甲状腺乳头状癌消融治疗后复发转移的危险因素(P<0.05).结论:甲状腺乳头状癌消融治疗后复发转移率较高,男性、病灶多发、肿瘤直径增大、紧贴包膜与超声引导下微波消融治疗甲状腺乳头状癌术后复发转移有关.
Prognosis and Influencing Factors of Ultrasound-guided Microwave Ablation in the Treatment of Papillary Thyroid Carcinoma
Objective:To investigate the prognosis and influencing factors of ultrasound-guided microwave ablation for papillary thyroid carcinoma.Method:The medical records of 132 patients with papillary thyroid carcinoma admitted to Shangrao Municipal Hospital from April 2018 to April 2020 were selected for retrospective analysis.All patients underwent microwave ablation under ultrasound guidance.The medical records of all enrolled patients were collected and organized,and outpatient follow-up data within 3 years were collected.Based on whether lymph node metastasis or recurrence was detected during the follow-up period,the patients were divided into the recurrence/metastasis group and the non-recurrence/non-metastasis group.The related factors affecting the recurrence and metastasis of papillary thyroid carcinoma after ablation were analyzed by logistic regression.Result:Among 132 patients with papillary thyroid carcinoma,26 cases(19.70%)had recurrence/metastasis,and 106 cases(80.30%)had non-recurrence/non-metastasis.The proportion of male,multiple lesions,maximum diameter of tumor≥10 mm,and close to the capsule in the recurrence/metastasis group were higher than those in the non-recurrence/non-metastasis group,the differences were statistically significant(P<0.05).The results of logistic regression analysis showed that male[OR=3.356,95%CI(1.006,11.189)],multiple lesions[OR=18.435,95%CI(3.919,86.715)],maximum tumor diameter≥10 mm[OR=88.053,95%CI(10.965,707.112)],and close to the capsule[OR=52.081,95%CI(9.975,271.929)]were risk factor for recurrence/metastasis of papillary thyroid carcinoma after ablation(P<0.05).Conclusion:The recurrence and metastasis rate of papillary thyroid cancer after ablation therapy is relatively high,and male patients,multiple lesions,increased tumor diameter,and tight adherence to the capsule are related to ultrasound-guided microwave ablation therapy for postoperative recurrence and metastasis of papillary thyroid cancer.

Papillary thyroid carcinomaMicrowave ablationRecurrence/metastasisInfluencing factors

陈声辉、余明、叶金平

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上饶市立医院普外二科 江西 上饶 334000

甲状腺乳头状癌 微波消融 复发转移 影响因素

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(26)