Etiological Analysis of Alveolar Lavage Fluid under Electronic Bronchoscope in Children with Community-acquired Pneumonia in Jiangxi Maternal and Child Health Hospital from July to October 2023
Objective:To analyze the detection of pathogenic bacteria in hospitalized children with community-acquired pneumonia(CAP).Method:Clinical data of 72 children with CAP from July to October 2023 in Jiangxi Maternal and Child Health Hospital were retrospectively analyzed.Electronic bronchoscopic alveolar lavage was performed on the children,and the alveolar lavage fluid was collected for targeted next-generation sequencing(tNGS).The detection of pathogenic bacteria was recorded,and the distribution of pathogenic bacteria with different gender,age,imaging results and clinical symptoms were analyzed.Result:115 strains of pathogenic bacteria were detected in 72 children with CAP,among which Mycoplasma pneumoniae(drug-resistant type)had the highest detection rate(51.30%),followed by Streptococcus pneumoniae(11.30%).There were no statistically significant differences in the detection of pathogenic bacteria in children of different genders(P>0.05).Virus infection was predominant in infantile period,the detection rate was 42.86%.Mycoplasma pneumoniae(drug-resistant type)infection were predominant in school stage and preschool stage,the detection rate were 64.52%and 55.36%,respectively.There were significant differences in Mycoplasma and virus infection among different age groups(P<0.05).The imaging results included pulmonary consolidation,double pneumonia,right lung inflammation,left pneumonia and pleural effusion,and the detection rate of Mycoplasma pneumoniae(drug-resistant type)were the highest,with the detection rates of 51.92%,50.00%,45.71%,63.16%and 40.00%,respectively.The detection rate of Mycoplasma pneumoniae(drug-resistant type)were the highest in children with cough and fever,and the detection rates were 51.75%and 56.70%,respectively.The detection rates of Mycoplasma pneumoniae(drug-resistant type type)and Streptococcal pneumoniae were the highest in children with expectoration,both of which were 37.50%.The detection rate of rhinovirus type in children with asthma was the highest,and the detection rate was 50.00%.Conclusion:In the alveolar lavage fluid samples of 72 children with CAP in our hospital,the detection rate of Mycoplasma pneumoniae(drug-resistant type type)is the highest,followed by Streptococcal pneumoniae.The pathogenic bacteria infection is closely related to age,virus infection is predominant in infantile period,Mycoplasma pneumoniae(drug-resistant type)infection are predominant in school stage and preschool stage.
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