Clinical Effect of Shenqi Fuzheng Liquid in Adjuvant Treatment of Severe Acute Pancreatitis
Objective:To investigate the clinical effect of Shenqi Fuzheng Liquid in adjuvant treatment of severe acute pancreatitis.Method:A total of 74 patients with severe acute pancreatitis admitted to the Gastroenterological Intensive Care Unit(GICU)of the Second People's Hospital of Nantong City between January 2019 and December 2022 were selected and divided into the observation group(37 cases)and the control group(37 cases)using the random number table method.Both groups of patients were given fluid resuscitation,acid suppression,inhibition of pancreatic secretion,inhibition of pancreatic enzyme activity and anti-infective treatment,as well as early enteral nutrition.The observation group was additionally given Shenqi Fuzheng Liquid for adjuvant treatment.The T lymphocyte subpopulation,enterogenic infection index concentration before treatment and after 14 days of treatment,ICU length of stay,and complication rate were compared between the two groups.Result:Before treatment,there were no statistically significant differences in cellular immune function between the two groups of patients(P>0.05);after treatment,the level of CD3+was(73.02±6.49)%and the level of CD4+was(57.09±5.04)%in the observation group,which were significantly higher than CD3+[(64.19±5.86)%]and CD4+[(47.62±4.35)%]in the control group;the CD4+/CD8+was(2.45±0.57)in the observation group,which was significantly higher than(2.11±0.62)in the control group,the differences were statistically significant(P<0.05).After 14 days of treatment,the levels of C reactive protein(CRP),procalcitonin(PCT)and endotoxin(ET)in the observation group were significantly lower than those in the control group,the incidence rates of respiratory failure,pancreatic infection and MODS in the observation group were significantly lower than those in the control group,and the ICU admission time in the observation group was shorter than that in the control group,with statistically significant differences(P<0.05).There were no statistically significant differences in the incidence rates of renal failure and pneumonia between the two groups(P>0.05).Conclusion:Administration of Shenqi Fuzheng Liquid to patients with severe acute pancreatitis could better improve the patient's cellular immune function,reduce the infection rate caused by enterogenous bacteria and the incidence of various complications,demonstrating its valuable application in clinical practice.
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