Effect of Modified Decompressive Craniectomy on Cerebral Blood Flow and Cerebral Oxygen Metabolism in Patients with Severe Craniocerebral Injury
Objective:To explore the therapeutic effect of modified decompressive craniectomy in severe craniocerebral injury and its impact on cerebral blood flow and cerebral oxygen metabolism.Method:A total of 120 patients with severe craniocerebral injury who received treatment at Jianli Traditional Chinese Medicine Hospital from January 2020 to January 2022 were selected and grouped according to their similarities and differences in treatment methods.Sixty patients underwent traditional decompressive craniectomy and were divided into the control group;sixty patients underwent modified decompressive craniectomy and were divided into the observation group.The national institutes of health stroke scale(NIHSS)scores,serum neuron specific enolase(NSE)levels,cerebral hemodynamic indicators,cerebral oxygen metabolism indicators and incidence of complications were compared between the two groups of patients.Result:After surgery,the NIHSS score,NSE level,bilateral internal carotid artery pulsatility index(PI)and internal carotid artery oxygen content(CaO2)of both groups decreased,those of the observation group were lower than those of the control group,and the maximum systolic blood flow velocity(Vs),average blood flow velocity(Vm),cerebral oxygen uptake rate(CERO2),internal jugular vein oxygen content(CjvO2)and jugular bulb venous oxygen saturation(SjvO2)all increased,those of the observation group were higher than those of the control group,the differences were statistically significant(P<0.05).The incidence of complications in the observation group(1.67%)was lower than that in the control group(11.67%),the difference was statistically significant(P<0.05).Conclusion:Modified decompressive craniectomy in patients with severe craniocerebral injury can alleviate nerve damage,improve cerebral hemodynamics and oxygen metabolism,reduce complications,and be safe and effective.
Severe craniocerebral injuryModified debridement decompressionNeurological functionCerebral hemodynamicsCerebral oxygen metabolism
万方数据
维普
