Discussion on the Theoretical Basis of Wujiajian Zhengqi Powder in the Treatment of IBS-D from the"Spleen Storing Idea"
The incidence of irritable bowel syndrome with diarrhea(IBS-D)remains high,and the brain-gut axis disturbance caused by mental and psychological abnormalities is an important pathogenic factor.Traditional Chinese medicine believes that"dysfunction of spleen in transportation"and"spleen not storing idea"are the key to the pathogenesis,the spleen is in the middle jiao,which is the"pivot"of the five zang viscera Qi movement and the foundation of emotion."Spleen storing idea"contains different connotations such as cognition,emotion and physiology,and is closely related to the brain-gut axis.It is not only an important part of the theory of Zang Xiang,but also a bridge between emotional diseases of traditional Chinese medicine and western medicine psychology.Wujiajian Zhengqi Powder can enhance immunity,regulate intestinal flora,anti-inflammation and diarrhea,regulate visceral hypersensitivity and other functions in multi-channel and multi-target through strengthening spleen idea and activating spleen nutrient.This paper discusses the theoretical basis of Wujiajian Zhengqi Powder in the treatment of IBS-D from the"spleen storing idea",provides a theoretical basis for further revealing the target of the regulation of brain-gut axis of this classical prescriptions,and provides new ideas and methods for treating digestive psychosomatic diseases from"spleen".
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