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疫苗临床研究中健康志愿者参与行为意向的影响因素分析

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目的:通过调查影响疫苗临床研究健康志愿者参与行为意向的因素,为后续疫苗临床研究志愿者招募和管理提供参考依据.方法:采取便利抽样法,于2023年3—5月对223名参与疫苗临床研究的健康志愿者进行问卷调查,采用多元线性回归分析疫苗临床研究健康志愿者参与行为意向的影响因素.结果:疫苗临床研究健康志愿者参与行为意向的总分平均为(15.56±4.13)分,健康志愿者对临床研究的了解程度和参与满意度是影响其参与行为意向的重要因素(P<0.05).结论:健康志愿者对临床研究的了解程度和参与满意度是影响其参与行为意向的重要因素,因此,在疫苗临床研究中应采取有效措施提高健康志愿者对研究的理解,并关注其在研究参与过程中的感受.
Analysis of Influence Factors of Behavioral Intention of Healthy Volunteers Participating in Vaccine Clinical Research
Objective:To investigate the factors that affect the intention of healthy volunteers to participate in a vaccine clinical trial,to provide reference basis for the recruitment management of subsequent vaccine clinical research.Method:The convenience sampling method was adopted to conduct a questionnaire survey on 223 healthy volunteers participating in vaccine clinical research from March to May 2023.Multiple linear regression was used to analyze the influencing factors on the behavioral intention of healthy volunteers participating in vaccine clinical research.Result:The average score of healthy volunteers' behavioral intention to participate in vaccine clinical research was (15.56±4.13) scores,and the understanding degree and satisfaction degree of healthy volunteers' participation in clinical research were important factors affecting their behavioral intention to participate (P<0.05).Conclusion:Healthy volunteers' understanding of clinical research and participation satisfaction are important factors affecting their behavioral intention to participate.Therefore,effective measures should be taken in vaccine clinical research to enhance volunteers' understanding of the research and pay attention to their feelings in participating in the research.

Healthy volunteersVaccine clinical trialBehavioral intentionInfluencing factor

袁慧、吴建元、罗琳、胡迪、周月菊、刘思、黄建英

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武汉大学中南医院Ⅰ期临床研究室 湖北 武汉 430071

健康志愿者 疫苗临床研究 行为意向 影响因素

2024

中国医学创新
中国保健协会

中国医学创新

影响因子:1.706
ISSN:1674-4985
年,卷(期):2024.21(32)