Effect of Phacoemulsification Combined with DEX-Ⅰ on Cataract Complicated with Diabetic Macular Edema
Objective:To explore the effect of phacoemulsification (Phaco) combined with Dexamethasone Intravitreal Implant (DEX-Ⅰ) in the treatment of cataract complicated with diabetic macular edema (DME). Method:A total of 149 cases of cataract complicated with DME in Shandong Lunan Eye Hospital from July 2022 to July 2023 were retrospectively analyzed. According to different treatment methods,they were divided into phacoemulsification with DEX-Ⅰ (Phaco-Dex) group (n=75) and phacoemulsification alone (Phaco) group (n=74). The clinical effect,best corrected visual acuity (BCVA),macular foveal retinal thickness,macular volume (MV) and complications. Result:The total effective rate of Phaco-Dex group was 82.67%,which was higher than 67.57% of Phaco group,the difference was statistically significant (P<0.05). Three months after operation,the BCVA of Phaco-Dex group was better than that of Phaco group,the difference was statistically significant (P<0.05). Three months after operation,the macular foveal retinal thickness and MV in the Phaco-Dex group were significantly lower than those in the Phaco group,the differences were statistically significant (P<0.05). Three months after operation,the incidence of complications in Phaco-Dex group was lower than that in Phaco group,the difference was statistically significant (P<0.05). Conclusion:Compared with patients treated with Phaco alone,Phaco combined with DEX-Ⅰ can improve the treatment efficiency,improve the vision of patients,improve the morphology of macular area and reduce the incidence of complications.
PhacoemulsificationDexamethasone Intravitreal ImplantDiabetic macular edemaCataractRetinal thickness of macular fovea