Etiological Characteristics and Risk Factors of Incision Infection in Patients after Radical Mastectomy
Objective:To investigate the etiological characteristics and risk factors of incision infection in patients after radical mastectomy. Method:A total of 110 breast cancer patients who underwent radical mastectomy in Ganzhou Cancer Hospital from January 2021 to December 2023 were selected as the study objects. The incidence of incisional infection and the distribution characteristics of pathogenic bacteria were analyzed,and the risk factors affecting the occurrence of incisional infection were analyzed. Result:Among the 110 patients who underwent radical mastectomy,a total of 14 cases developed incision infection,with an incidence of 12.73％;a total of 25 strains of pathogenic bacteria were detected,among which Gram-negative bacteria accounted for 60.00％,Gram-positive bacteria and fungi accounted for 32.00％ and 8.00％ respectively. Univariate analysis showed that there were statistically significant differences in the incidence of postoperative incision infection among patients with different ages,diabetes mellitus,operation time,drainage tube retention time,postoperative prophylactic antibiotics and adjuvant chemotherapy (P<0.05). There were no significant differences in the incidence of postoperative incision infection among patients with different body mass index,combined hypertension,tumor diameter,tumor node metastasis (TNM) classification,intraoperative blood loss and drainage volume (P>0.05). Multivariate logistic regression analysis showed that age ≥60 years old,operation time ≥2 h,drainage tube retention time ≥7 d and adjuvant chemotherapy were the risk factors for postoperative incision infection (P<0.05). Conclusion:The pathogenic bacteria of incision infection in patients after radical mastectomy are mainly Gram-negative bacteria,the age ≥60 years,the operation time ≥2 h,the indentation and drainage time ≥7 d,and adjuvant chemotherapy are the main risk factors. Targeted prevention and control should be strengthened in clinical practice to reduce the incidence of incision infection.
Breast cancerRadical mastectomyIncision infectionEtiological characteristicsRisk factor
万方数据
维普
