Differential Diagnostic Value of C-TI-RADS Classification Combined with Contrast-enhanced Ultrasound in Benign and Malignant Thyroid Nodules
Objective:To explore the differential diagnostic value of Chinese thyroid imaging reporting and date system (C-TI-RADS) classification combined with contrast-enhanced ultrasound in benign and malignant thyroid nodules. Method:A total of 60 patients with thyroid nodules (154 nodules) admitted to Xiamen Haicang Hospital from January to December 2023 were selected. All patients underwent C-TI-RADS classification and contrast-enhanced ultrasound,and the result of pathological examination was regarded as the "gold standard" for diagnosis. The distribution of thyroid nodules in C-TI-RADS classification was recorded,and the value of C-TI-RADS classification and contrast-enhanced ultrasound alone and combined in the diagnosis of malignant thyroid nodules and the consistency with pathological examination were analyzed. Result:Pathological examination showed that 96 of the 154 nodules were benign and 58 were malignant. In the C-TI-RADS classification,the malignant rates of 3,4A,4B,4C and 5 nodules were 1.67％,36.36％,71.11％,78.57％ and 100％,respectively. The sensitivity,specificity,accuracy and Kappa value of C-TI-RADS classification in the diagnosis of malignant thyroid nodules were 77.59％,83.33％,81.17％ and 0.603,respectively. The sensitivity,specificity,accuracy and Kappa value of contrast-enhanced ultrasound in the diagnosis of malignant thyroid nodules were 84.48％,85.42％,85.06％ and 0.687,respectively. The sensitivity,specificity,accuracy and Kappa value of combined diagnosis of malignant thyroid nodules were 94.83％,95.83％,95.45％ and 0.904,respectively. The specificity and accuracy of combined diagnosis were significantly higher than those of single diagnosis,and the sensitivity was significantly higher than that of single C-TI-RADS classification diagnosis (P<0.05). Conclusion:Compared with C-TI-RADS classification or contrast-enhanced ultrasound alone,the combined application of both can significantly improve the diagnostic accuracy of malignant thyroid nodules.
万方数据
维普
