Diagnostic Value of Multimodal Ultrasound Combined with NT and Head-buttocks Length in Fetus with Suspected Cardiac Malformation in Second Trimester
Objective:To explore the diagnostic value of multimodal ultrasound combined with nuchal translucency (NT) measurement and head-buttocks length in fetuses with suspected cardiac malformations in the second trimester. Method:A review of 102 pregnant women with suspected cardiac malformations admitted to Fuzhou Municipal Hospital from January 2022 to December 2023 in the second trimester were reviewed,and multimodal ultrasound,NT and head-buttocks length examinations were performed in the second trimester,and the results of embryo pathological anatomy and follow-up after induction of labor were used as the gold standard for judging fetal cardiac malformations,and the value of multimodal ultrasound and NT measurement and head-buttocks length in diagnosing fetuses with cardiac malformations in the second trimester was analyzed. Result:Gold standard diagnostic results showed that 32 fetuses had suspected cardiac malformation in the second trimester. The fetal head-buttocks length and NT thickness of cardiac malformationswere (68.65±8.54) mm and (7.86±1.32) mm. The fetal head-buttocks length and NT thickness of non-cardiac malformations were (56.43±5.52) mm and (1.54±0.30) mm. The lengths of head and NT thickness were higher than those with non-cardiac malformations (P<0.05). The results of multimodal ultrasound were in good agreement with the gold standard (Kappa=0.697,P<0.05). The results of NT were in excellent agreement with the gold standard (Kappa=0.824,P<0.05). The head-buttocks length was consistent with the gold standard results (Kappa=0.721,P<0.05). The results of the combined diagnosis were in good agreement with the gold standard diagnosis (Kappa=0.910,P<0.05). The accuracy of multimodal ultrasound combined with NT and head-buttocks length in fetuses with suspected cardiac malformations in the second trimester was higher than that of a single diagnosis (P<0.05). Conclusion:The multimodal ultrasound combined with NT,head-buttocks length has a high diagnostic value for fetuses with suspected cardiac malformations in the second trimester.