Clinical Study of Methotrexate Combined with Laparoscopic Surgery for Patients with Extrauterine Pregnancy
Objective:To explore the effect of Methotrexate combined with laparoscopic surgery on the decrease rate of human chorionic gonadotropin (hCG) and intrauterine pregnancy rate in extrauterine pregnancy.Method:According to the method of random number table,102 extrauterine pregnancy patients admitted to the Gynecology Department of Fuzhou Maternal and Child Health Hospital from June 2022 to June 2023 were divided into study group (51 cases) and control group (51 cases).The control group was treated with laparoscopic surgery.On the basis of the control group,the study group was treated with Methotrexate.The hCG level,the decrease rate of hCG and time for hCG to return to normal,clinical efficacy,time of mass disappearance,hospital stay,menstrual recovery time,adverse reactions and intrauterine pregnancy within 1 year after surgery were compared between the two groups.Result:After treatment,the hCG level in the study group was lower than that in the control group,the recovery time of hCG was shorter than that in the control group,and the hCG decreasing rate was higher than that in the control group,the differences were statistically significant (P<0.05).The total effective rate of the study group was higher than that of the control group,the difference was statistically significant (P<0.05).The time of mass disappearance,hospital stay and menstrual recovery in the study group were shorter than those in the control group,the differences were statistically significant (P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).The rate of intrauterine pregnancy 1 year after surgery in the study group was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion:The treatment of patients with ectopic pregnancy with Methotrexate combined with laparoscopic surgery can effectively reduce the hCG level,shorten the time for hCG to return to normal,and accelerate the recovery of patients,which is conducive to improving the intrauterine pregnancy rate and hCG decline rate,with accurate effects and high safety,worthy of promotion and application.
Extrauterine pregnancyMethotrexateLaparoscopic surgeryDecrease rate of hCGIntrauterine pregnancy rate
万方数据
维普
