Prognostic Evaluation Value of PLR and SOFA Score in Elderly Patients with Sepsis Combined with Corona Virus Disease 2019
Objective:To explore the prognostic value of platelet to lymphocyte count ratio (PLR) combined with sequential organ failure assessment (SOFA) score in elderly sepsis patients with COVID-19.Method:A total of 82 elderly patients with sepsis combined with COVID-19 hospitalized in Department of Critical Care Medicine,Cardiovascular and Cerebrovascular Disease Hospital,General Hospital of Ningxia Medical University from December 2022 to February 2023 were collected and divided into survival group and death group according to 28-day clinical outcomes.The clinical indicators,laboratory indicators,SOFA,acute physiology and chronic health evaluation Ⅱ (APACHEⅡ),neutrophil to lymphocyte ratio (NLR) and PLR of the two groups were statistically analyzed.logistic regression was used to analyze the PLR and SOFA score of 28-day death in elderly patients with sepsis combined with COVID-19,and receiver operating characteristics (ROC) curve was drawn to evaluate the value of PLR and SOFA score in prognostic assessment.Result:Of the 82 patients,38 survived and 44 died within 28 days.Respiratory rate,SOFA score,APACHEⅡ,NLR and PLR in death group were higher than those in survival group,and lymphocyte in death group was lower than that in survival group,the differences were statistically significant (P<0.05).logistic regression analysis showed that APACHEⅡ,SOFA scores and PLR level were influencing factors for 28-day death in elderly patients with sepsis combined with COVID-19 (P<0.05).ROC curve results showed that PLR combined with SOFA score had high predictive efficacy for 28-day death in elderly patients with sepsis combined with COVID-19,and the AUC was 0.891,sensitivity was 84.1％,and specificity was 81.6％.Conclusion:SOFA score and PLR level are influencing factors for 28-day death in elderly patients with sepsis combined with COVID-19,and PLR combined with SOFA score has a high predictive value in 28-day death in elderly patients with sepsis combined with COVID-19.
万方数据
维普
