Analysis of High Risk Factors of Non-curative Resection in Patients with Early Colorectal Cancer Treated with ESD
Objective:To explore the high risk factors of non-curative resection in patients with early colorectal cancer treated with endoscopic submucosal dissection (ESD).Method:The clinical data of 102 patients with early colorectal cancer admitted to Suzhou Ninth People's Hospital from January 2021 to January 2024 were retrospectively analyzed.Patients were divided into occurrence group (n=29) and non-occurrence group (n=73) according to whether non-curative resection was performed.Age,gender,tumor morphology,tumor diameter,tumor location,pathological type,infiltration depth,intraoperative bleeding volume,intraoperative perforation and scar lesions of the two groups were collected.logistic regression analysis was performed to determine the high risk factors for non-curative resection in early patients with early colorectal cancer treated with ESD.Result:Among 102 patients,29 were non-curative resection,the incidence rate of 28.43％.There were significant differences in tumor morphology,tumor diameter,infiltration depth,intraoperative bleeding volume,intraoperative perforation and scar lesions between the two groups (P<0.05).Multivariate analysis showed that ulcerative[OR=4.831,95％CI (1.908,12.230)],tumor diameter ≥40 mm[OR=3.648,95％CI (1.475,9.023)],infiltration of submucosa[OR=4.130,95％CI (1.661,10.273)],intraoperative bleeding volume ≥10 mL[OR=4.336,95％CI (1.775,10.768)],intraoperative perforation[OR=7.762,95％CI (2.161,27.881)],scar lesions[OR=2.852,95％CI (1.157,7.029)]were high risk factors for non-curable resection (P<0.05).Conclusion:Non-curative resection of early colorectal cancer patients after ESD treatment is closely related to tumor morphology,tumor diameter,infiltration depth,intraoperative bleeding volume,intraoperative perforation and scar lesions.
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