Evaluation of the correlation between vulnerability and distribution location of carotid plaque based on CTA
[Objective]To analyze the relationship among distribution location,characteristics,and vulnerability of carotid plaque using CTA and provide more information on the risk factors and formation mechanism of carotid atherosclerotic plaque.[Methods]We retrospectively analyzed the CTA images of the head and neck of 89 patients with carotid atherosclerosis.Atherosclerosis was developed in 144 carotid arteries.The plaques were divided into a high-risk plaque group and a low-risk plaque group according to whether the plaques had high-risk characteristics,and the differences in the characteristics and distribution locations of the plaques in the two groups were analyzed.The characteristic parameters of the cross-sectional plaques at the bifurcation of the carotid artery,including the thickness,remodelling index and distribution location of the plaques(ventral,dorsal,inner,and outer side walls)etc.were measured.[Results]Among 144 carotid arteries,79 were classified as high-risk and 65 as low-risk groups.There were significant differences between the two groups concerning the thickness,length,maximum cross-sectional area,burden,and cross-sectional distribution of the plaques(P<0.05).The plaque distribution on the dorsal side wall of the carotid bifurcation was higher in the high-risk group than that in the low-risk group(P<0.05).The plaque distribution on the outer wall of the carotid bifurcation was higher in the low-risk group than in the high-risk group(P<0.05).[Conclusion]High-risk plaques tend to occur on the dorsal side wall of the carotid bifurcation,whereas low-risk plaques tend to occur on the outer side wall of the carotid bifurcation.