[Objective]To investigate the risk factors of subchorionic hematoma(SCH)in pregnant women with threatened abortion in early pregnancy and its adverse effect on pregnancy outcome.[Methods]Eighty-nine pregnant women with threatened abortion complicated with SCH who visited the Third Affiliated Hospital of Zhengzhou University from January 2021 to June 2022 were retrospectively collected as SCH group,and 106 pregnant women with threatened abortion who visited the Third Affiliated Hospital during the same period were selected as normal group.Immunological indicators,pregnancy complications and pregnancy outcomes such as miscarriage,premature and full-term births,and newborns in both groups were analyzed.[Results]Serological test results between the two groups showed that the serum homocysteine level,the positive rates of lupus anticoagulant,anti-phospholipid antibody and anti-nuclear antibody spectrum in SCH group were higher than those in normal group,with statistical significance(P＜0.05).The activity of protein S and protein C,antithrombin Ⅲ(AT-Ⅲ)were lower than those in normal group,with statistical significance(P＜0.05).The rate of premature rupture of membranes,fetal distress rate and abortion rate in SCH group were higher than those in normal group,while the gestational week of fetal delivery and fetal birth weight were lower than those in normal group,and the difference was statistically significant(P＜0.05).[Conclusion]Positive autoantibody during pregnancy is a risk factor for SCH,and SCH may lead to adverse pregnancy outcomes such as abortion,lower gestational age and lower birth weight.
维普
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