Prediction model construction of differential diagnosis of primary thyroid lymphoma based on ultrasonic characteristics
[Objective]To investigate the prediction index of differential diagnosis of primary thyroid lymphoma and construct prediction model based on ultrasonic characteristics to provide more reference for the early differential diagnosis and treatment of invasive lung adenocarcinoma.[Methods]Forty-seven patients with primary thyroid lymphoma and 50 patients with undifferentiated thyroid cancer were retrospectively chosen in the period from January 2014 to January 2023.The clinicopathological and ultrasonic features of the two groups were compared,and the prognostic factors for differential diagnosis of primary thyroid lymphoma were evaluated by univariate and multivariate analysis method.Construction and efficacy analysis of differential diagnosis prediction model for primary thyroid lymphoma were done.[Results]There were significant differences in the proportion of combined Hashimoto's thyroiditis,lesion type,internal echo type,calcification ratio,cystic change ratio and posterior echo enhancement ratio between the two groups(P＜0.05).The results of multivariate analysis showed that whether Hashimoto's thyroiditis was complicated,lesion type,internal echo type,posterior echo enhancement,calcification and cystic change could be used as independent predictors for differential diagnosis of primary thyroid lymphoma(P＜0.05).The independent influencing factors of the regression model and the prediction probability of P-value were used to predict the risk of primary thyroid lymphoma of the patients,and the Youden index was 53.70％,37.84％,79.90％,77.74％,35.49％,82.70％,92.33％,respectively.[Conclusion]The presence or absence of Hashimoto thyroiditis,lesion type,internal echo type,posterior echo enhancement,calcification and cystic change can guide the diagnosis of primary thyroid lymphoma.The prediction model based on ultrasonic characteristics has satisfactory efficacy in the differential diagnosis of primary thyroid lymphoma and undifferentiated thyroid carcinoma.
万方数据
维普
