Diagnostic value of ultrasound-guided fine needle aspiration cytology combined with thyroglobulin for metastatic lymph nodes in lateral cervical region of papillary thyroid carcinoma
[Objective]To investigate the diagnostic value of ultrasound-guided fine needle aspiration cytology(FNAC)combined with thyroglobulin(FNA-Tg)for metastatic lymph nodes(MLN)in the lateral cervical region of papillary thyroid carcinoma(PTC),in order to provide a plan for clinical early screening and diagnosis.[Methods]Totally 128 patients with PTC suspected MLN in the lateral cervical region from January 2022 to December 2022 were selected as the study subjects.After admission,all patients were examined by FNAC and FNA-Tg,the ultrasonographic characteristics of MLN in the cervical region of PTC were analyzed;the pathological result was used as the"gold standard",the diagnostic values of FNAC,FNA-Tg alone and combined detection for MLN in the lateral cervical region of PTC were compared.[Results]Pathological diagnosis showed that there were 92 positive cases and 36 negative cases;the FNAC diagnosis results showed that there were 81 positive cases and 47 negative cases;the FNA-Tg diagnosis results showed that there were 78 positive cases and 50 negative cases;the results of FNAC and FNA-Tg combined diagnosis showed that there were 91 positive cases and 37 negative cases.The sensitivity and accuracy of FNAC and FNA-Tg combined diagnosis were 95.65％and 94.53％,respectively,which were higher than those of FNAC alone diagnosis(84.78％,86.72％)and FNA-Tg alone diagnosis(82.61％,85.94％),the missed diagnosis rate was 4.35％,which was obviously lower than that of FNAC alone diagnosis(15.22％)and FNA-Tg alone diagnosis(17.39％),the difference was significant(P＜0.05).The detection rate of MLN in region Ⅱ by FNAC and FNA-Tg combined detection was 100％,which was higher than that by FNAC alone detection(72.22％)and FNA-Tg alone detection(72.22％),the difference was significant(P＜0.05).[Conclusion]The combined detection of FNAC and FNA-Tg can effectively improve the diagnostic accuracy and sensitivity of MLN in the lateral cervical region of PTC,reduce the missed diagnostic rate,and provide a basis for early clinical screening diagnosis and treatment plan.
万方数据
维普
