Relationship between expression of preoperative albumin/ferritin ratio and occurrence of early abdominal hemorrhage after radical surgery for advanced gastric cancer
[Objective]To investigate the relationship between the expression of albumin/ferritin ratio before operation and the occurrence of early abdominal hemorrhage after radical surgery for advanced gastric cancer.[Methods]A case-control study was conducted,the clinical data of 22 patients with advanced gastric cancer who underwent early abdominal hemorrhage after radical gastrectomy in Xinyang Central Hospital of Henan Province from February 2021 to November 2022 were collected and included into the occurrence group.In addition,the clinical data of 44 patients with advanced gastric cancer who did not have early postoperative abdominal hemorrhage during the same period were collected and included in the non-occurrence group.By consulting the medical records and follow-up data of patients with advanced gastric cancer,the baseline data such as age,sex,primary lesion location,disease type,and operation time were recorded.The levels of albumin,ferritin,carcinoembryonic antigen(CEA),carbohydrate antigen(CA199),glycosylated hemoglobin and total cholesterol were measured before operation,and the albumin/ferritin value was calculated.The relationship between the level of albumin/ferritin and the occurrence of early abdominal hemorrhage after radical resection of advanced gastric cancer was analyzed.[Results]Albumin and albumin/ferritin in the occurrence group were significantly lower than those in the non-occurrence group,with a statistical significant difference(P<0.05).There was no statistical significant difference in the baseline data of age,sex,disease type,primary focus and other laboratory indicators between the groups(P>0.05).The results of point two column correlation showed that albumin and albumin/ferritin were negatively correlated with early abdominal hemorrhage after radical gastrectomy for advanced gastric cancer(r<0,P<0.05).The ROC curve was drawn.The results showed that the AUC value of preoperative albumin/ferritin in predicting the occurrence of early abdominal hemorrhage after radical resection of advanced gastric cancer was 0.723,which had certain predictive power.[Conclusion]Albumin/ferritin is associated with early abdominal hemorrhage after radical resection of advanced gastric cancer.The lower the albumin/ferritin value,the greater the possibility of postoperative abdominal hemorrhage.